Dimenhydrinate | 523-87-5

Description :

Overview of Dimenhydrinate

Dimenhydrinate is an antihistamine as well as an anticholinergic medication used to treat and manage nausea, motion sickness, vertigo and vomiting. The drug is renowned for its vestibular suppressant as well as antiemetic effects. Dimenhydrinate is widely used for travel-related medicine as well as to treat emetic issues.

This API appears as a white to off-white crystalline powder with good stability under standard storage conditions. Its mechanism—antagonism of histamine H1 receptors and muscarinic receptors—suppresses vestibular stimulation and reduces nausea and vomiting associated with motion and other causes.

Related products include Meclizine, Promethazine, Ondansetron, and other antiemetic and antihistamine agents used to manage motion sickness and nausea.

Applications of Dimenhydrinate

Pharmaceutical API

• Used in antiemetic and motion sickness medications
• Effective in preventing and treating nausea, vomiting, and dizziness
• Used for vertigo associated with Ménière's disease
• Applied to radiation sickness and postoperative nausea

Formulation Development

• It is used to make tablets, chewable tablets, liquid solutions and Suppositories
• In immediate-release as well as extended-release versions
• Ideal for use in pediatric as well as adult formulations
• Offers excellent stability across various dosage forms

Travel Medicine & Antiemetic Treatment

• Reduces motion sickness in journeys (car, boat, and plane)
• Eliminates nausea and vomiting caused by a myriad of reasons
• It has a sedative effect that is beneficial to those with anxiety about travel.
• Rapid-acting, with a time span of 3 to 6 hours

Safety & Handling Guidelines

• Do not inhale fine powder
• Make sure you wear gloves, goggles, or protective clothing while handling
• Keep it in a dry, cool location away from light and humidity
• Be sure to follow COA and MSDS directions strictly

Where to Buy Dimenhydrinate?

Dimenhydrinate Manufacturer

ChemicalBull supplies high-purity Dimenhydrinate API that meets IP/EP/USP quality standards for pharmaceutical formulations.

Dimenhydrinate Supplier & Distributor

• Available in bulk packing for formulation units
• Stable and high-purity grade for research and production
• COA, MSDS, and regulatory documents provided

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is the structure of Dimenhydrinate?
   

   Dimenhydrinate is the 8-chlorotheophyllinate salt of diphenhydramine, with molecular formula C₂₄H₂₈ClN₅O₃, combining antihistamine and mild stimulant properties.
   
   

2. What is Dimenhydrinate medicine?
   

   Dimenhydrinate is an antihistamine medication primarily used to prevent and treat motion sickness, nausea, vomiting, and vertigo.
   
   

3. Is Dimenhydrinate India available?
   

   Yes, Dimenhydrinate is widely available in ChemicalBull India under various brand names for motion sickness and antiemetic indications.
   
   

4. Is Dramamine the same as Gravol?
   

   Both Dramamine and Gravol contain Dimenhydrinate as the active ingredient; they are the same medication sold under different brand names in different regions.