Beta Caryophyllene Oxide | 1139-30-6

Description :

Overview of Beta-Caryophyllene Oxide

Beta-Caryophyllene Oxide is a crystalline solid or liquid that is colourless to pale yellow. It has a woody, spicy, and slightly herbal smell. It is an epoxidised version of beta-caryophyllene, which is a sesquiterpene found in the essential oils of many aromatic plants, such as clove, black pepper, oregano, rosemary, cannabis, and others. It has the molecular formula C₁₅H₂₄O, and it can be made by extracting it from plants or by chemically oxidising beta-caryophyllene. It is a tricyclic sesquiterpenoid, which means it has a structure that is very similar to Alpha-Humulene and Bisabolol.

Applications of Beta-Caryophyllene Oxide

Flavour & Fragrance Industry

Beta-Caryophyllene Oxide imparts a complex, woody-spicy note to fine fragrances, incense, and flavour blends. It functions as a middle or base note, adding depth to perfumes and aroma compositions. The compound is often formulated with related terpenoids such as Alpha-Humulene and Linalool, supporting multidimensional olfactive design. In food flavouring, it is sometimes used to mimic the aroma of black pepper, herbs, or spice mixes.​

Essential Oils and Personal Care

Beta-Caryophyllene Oxide is present as an active ingredient in many essential oils—clove, cannabis, guava leaf, melissa, and geranium rose-scented oils, among others. Its antimicrobial and aroma-enhancing properties make it desirable in cosmeceutical creams, balms, and anti-dandruff shampoos, often alongside Bisabolol and Limonene.​

Pharmaceutical & Therapeutic Research

Experimental studies reveal beta-caryophyllene oxide as a bioactive compound with significant anti-inflammatory, antioxidant, analgesic, anticancer, antiviral, and genoprotective activities. It is a potent inhibitor of drug-metabolising enzymes (especially cytochrome P450 3A family), and demonstrates antifungal and antibacterial effects. 

Agricultural and Technical Use

Due to its antimicrobial activity, beta-caryophyllene oxide is evaluated as a natural crop protectant or biopesticide, especially when formulated in blends with essential oils for disease and pest management. 

Safety & Handling Guidelines

• Beta-Caryophyllene Oxide has low toxicity via ingestion and skin contact, but skin irritation can occur with prolonged or concentrated exposure.​
• Always wear gloves and safety goggles, and use in well-ventilated areas; avoid direct inhalation, ingestion, or eye contact.​
• Store in tightly sealed containers at cool temperatures, protected from light and strong oxidisers; maintain stability by minimising exposure to air and heat.​
• Wash your hands after handling and avoid eating, drinking, or smoking in work areas.​
• For spills, absorb with inert material and ventilate the area thoroughly; beta-caryophyllene oxide can emit acrid smoke and irritating fumes if heated to decomposition.​
• Waste and unused material should be disposed of per local environmental regulations; prevent release to water bodies and drains.​
• Request and review the Material Safety Data Sheet (MSDS) before bulk use, especially in research or manufacturing settings.​
  
  

Where to Buy Beta-Caryophyllene Oxide?

Beta-Caryophyllene Oxide Manufacturer in India

ChemicalBull offers natural and synthesised beta-caryophyllene oxide of high purity for fragrance, flavour, personal care, and research applications.

Distributor & Supplier 

ChemicalBull reliably supplies bulk and small quantities of beta-caryophyllene oxide with full documentation for cosmetic, technical, and research deployment.

Beta-Caryophyllene Oxide MSDS

Detailed safety, toxicity, environmental, and storage data are available via the Material Safety Data Sheet (MSDS) from ChemicalBull.

Frequently Asked Questions

1. What is beta-caryophyllene oxide used for?
   

   It is used in fragrances, flavourings, essential oils, pharmaceuticals, and agricultural formulations for its aroma, bioactivity, and antimicrobial effects.​
   
   

2. Is beta-caryophyllene oxide safe?
   

   It is generally regarded as safe with low toxicity but may cause mild skin irritation; follow all safety guidelines and recommended concentrations.​
   
   

3. Is beta-caryophyllene oxide naturally occurring?
   

   Yes, it occurs in trace amounts in many essential oils and is also obtained by oxidation of beta-caryophyllene from plant sources.