Baclofen | 1134-47-0

Description :

Overview of Baclofen

Baclofen is a pharmaceutical-grade centrally acting muscle relaxant widely used in the management of spasticity associated with neurological disorders. It is a gamma-aminobutyric acid (GABA) derivative known for its targeted action on the central nervous system.

In the pharmaceutical industry, Baclofen is valued for its proven efficacy in reducing muscle tone, improving mobility, and supporting neurological rehabilitation. Pharmaceutical-grade Baclofen is manufactured under controlled conditions to meet regulatory standards for oral and intrathecal formulations.

As a pharmaceutical chemical, Baclofen plays an important role in neuromuscular and neurological therapy.

Applications of Baclofen

Neurological & Muscle Relaxant Use

Baclofen uses include the treatment of muscle spasticity caused by conditions such as multiple sclerosis, spinal cord injury, and cerebral palsy. It helps relieve muscle stiffness, spasms, and associated pain.

In neuromuscular formulations, it is often evaluated alongside Tizanidine Hydrochloride for spasticity management.

Pharmaceutical Chemistry & Mechanism of Action

The baclofen mechanism of action involves activation of GABA-B receptors in the spinal cord and brain, which inhibits excitatory neurotransmitter release and reduces muscle hyperactivity.

In pharmacological research, Baclofen is compared with agents such as Diazepam for central muscle relaxant effects.

Clinical & Pharmaceutical Use

Baclofen is administered orally or intrathecally under medical supervision. It is widely used in hospital and rehabilitation settings and is often included in comprehensive neurological treatment protocols with supportive agents such as Gabapentin.

Safety & Handling Guidelines

• Store in a cool, dry, and controlled environment
• Keep containers tightly sealed and clearly labelled
• Avoid inhalation of dust during handling
• Avoid direct contact with skin and eyes
• Use protective gloves and pharmaceutical-grade protective clothing
• Handle under controlled pharmaceutical manufacturing conditions
• Dispose of waste according to regulatory guidelines
  
  
  

Where to Buy Baclofen?

Baclofen Manufacturer

Baclofen is manufactured for pharmaceutical applications where high purity, consistent potency, and compliance with neurological drug standards are essential.

Baclofen Supplier & Distributor

Baclofen is supplied in pharmaceutical-grade packaging for formulation manufacturers and healthcare institutions. As a pharmaceutical chemicals supplier and distributor, Chemicalbull Pvt. Ltd. supports customers with reliable sourcing and standard documentation.

MSDS for Baclofen

The MSDS for Baclofen provides detailed information on hazards, safe handling practices, storage conditions, exposure controls, first-aid measures, and emergency response procedures. Always review the MSDS before pharmaceutical use.

Frequently Asked Questions (FAQs)

1. What is Baclofen used for?
   

   Baclofen is used to treat muscle spasticity caused by neurological conditions such as multiple sclerosis and spinal cord injury.
   
   

2. What is the chemical name of Baclofen?
   

   The chemical name of Baclofen is (4-amino-3-(4-chlorophenyl)butanoic acid).
   
   

3. What are the common side effects of Baclofen?
   

   Common baclofen side effects include drowsiness, dizziness, weakness, fatigue, and nausea, especially during dose initiation.