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Adapalene | 106685-40-9

Cas No :

106685-40-9

Form :

Powder

Molecular Weight :

412,52 G/Mol

Molecular Formula :

C28H28O3

Melting Point :

319 - 322 °C

Solubility :

Dmso, Methanol

Description :

Overview of Adapalene

Adapalene is an off-white or off-white crystalline powder that belongs to the class of retinoid chemicals, extensively used in skincare and dermatology formulations. Its primary purpose is to be a gel for topical use or a cream that treats blackheads, acne vulgaris, and blocked pores. In its third generation as a synthetic retinoid, it is a skin cell stimulator that regulates differentiation, keratinization, and inflammation processes. It also prevents the development of acne-related lesions. The drug is known for its outstanding quality, stability, and mild irritation. Adapalene is a preferred option for dermatologists as well as skin care professionals. Complementary compounds such as Fenchyl Alcohol and Phytol are often used in related cosmetic and pharmaceutical formulations for enhanced skincare performance. It is available in both trim and bulk packaging — contact us to get the best price for your order.

 

 

Applications of Adapalene

Pharmaceutical & Dermatology Industry

Adapalene is primarily used as an active pharmaceutical ingredient in topical formulations such as Adapalene Gel 0.1% or 0.3%, prescribed for acne treatment. It works by preventing the buildup of dead skin cells and reducing inflammation associated with acne.

 

Cosmetics & Personal Care

Due to its mild retinoid action, Adapalene is incorporated into dermatological skincare products designed to improve skin texture, tone, and clarity. It helps reduce the appearance of fine lines and acne scars.

 

Research & Development

Used in pharmaceutical R&D to study retinoid receptor activity, skin regeneration, and anti-inflammatory pathways in dermatological treatments. Complementary skincare compounds like Rosalva and Ethyl Oleate are also applied in similar product developments for improved formulation stability and absorption.

 

 

Safety & Handling Guidelines

  • Always wear gloves, goggles, and protective clothing when handling Adapalene in concentrated form.

  • Avoid inhalation or prolonged contact with skin.

  • Handle in a well-ventilated environment.

  • Store in tightly sealed containers in a cool, dry, and dark place away from light and heat.

  • Dispose of waste materials according to local pharmaceutical and environmental regulations.

 

 

Where to Buy Adapalene?

Adapalene Manufacturer in India:

ChemicalBull manufactures pharmaceutical-grade Adapalene suitable for use in topical dermatological formulations. Each batch undergoes stringent quality testing to ensure purity, efficacy, and stability.

 

Adapalene Distributor in Noida:

Available in bulk and laboratory-grade packaging with safe, timely delivery across Noida. ChemicalBull's logistics network ensures reliable and professional distribution for pharmaceutical and cosmetic manufacturers.

 

Adapalene Supplier in Noida:

Delivered in moisture-proof, secure containers with customizable order quantities for both small-scale laboratories and large-scale manufacturers. Explore more Pharmaceutical Intermediates and Fine Chemicals for your product formulation and skincare development needs.

 

 

Adapalene MSDS

For detailed information on toxicity, safety data, and handling procedures, request the official Material Safety Data Sheet (MSDS) for Adapalene from ChemicalBull.

 

 

Frequently Asked Questions

  1. How to use Adapalene gel?

    Adapalene gel should be applied once daily in the evening to clean, dry skin. Use a thin layer over the entire affected area, avoiding the eyes, lips, and mucous membranes. Consistent use helps prevent new acne breakouts.



  2. Is Adapalene a retinoid?

    Yes, Adapalene is a third-generation synthetic retinoid. It works by binding to specific retinoic acid receptors in the skin to normalize cell turnover, unclog pores, and reduce inflammation.


  3. How to apply Adapalene gel?

    Cleanse your face gently and pat dry before application. Apply a pea-sized amount of Adapalene gel evenly across the affected area once daily at night. Avoid applying excessive amounts to prevent irritation or dryness.

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