Adapalene | 106685-40-9

Cas No :

106685-40-9

Form :

Powder

Molecular Weight :

310.39 G/Mol

Molecular Formula :

C28H28O3

Boiling Point :

217.8 °C

Melting Point :

100.0 °C

Flash Point :

210.0 °C

Solubility :

Practically Insoluble In Water; Soluble In Organic Solvents Such As Ethanol, Methanol, Acetone, And Dmso

Description :

Overview of Adapalene

Adapalene is a third-generation retinoid widely used in dermatology for acne treatment. It works by regulating skin cell turnover, preventing clogged pores, and reducing inflammation, promoting clearer and healthier-looking skin. Adapalene is known for its stability, lower irritation compared to older retinoids, and excellent efficacy in topical formulations such as gels, creams, and lotions.

Adapalene is the standard globally accepted name for this compound and is commonly referenced in pharmacopeia guidelines, dermatological product regulations, cosmetic formulations, and safety data sheets.


Applications of Adapalene

Pharmaceutical & Dermatology Formulations

Adapalene is used in acne gels, creams, and lotions for treating mild to moderate acne. It is often combined with ingredients like Benzoyl Peroxide, Clindamycin, and Salicylic Acid to enhance therapeutic effects.


Cosmetic & Personal Care Industry

Used in anti-acne creams, serums, and skin-renewal formulations, Adapalene improves skin texture and reduces blemishes. It is compatible with Glycerin, Aloe Vera Extract, and Hyaluronic Acid in topical cosmetic products.


Combination Formulations

Applied in combination therapies for extended acne care, including formulations with antibiotics or exfoliating agents, providing synergistic effects for skin clarity and reduced irritation.


Safety & Handling Guidelines

  • Store in a cool, dry, well-ventilated place

  • Keep containers tightly sealed to avoid contamination

  • Avoid inhalation of powder; use appropriate respiratory protection

  • Use gloves, goggles, and protective clothing

  • Refer to the MSDS for complete guidelines on hazards, first aid, and disposal


Where to Buy Adapalene?

Adapalene Manufacturer

High-purity Adapalene is manufactured for pharmaceutical-grade, dermatology-grade, and cosmetic-grade applications. Production ensures consistent quality, stability, and compliance with global standards.


Adapalene Supplier & Distributor

ChemicalBull supplies Adapalene in reliable bulk packaging suitable for pharmaceutical companies, cosmetic brands, research labs, and international customers. Complete documentation, COA, MSDS, and export-quality packing are available.


MSDS for Adapalene

The MSDS covers chemical properties, exposure guidelines, toxicology details, handling precautions, accidental release measures, and first-aid instructions. Reviewing the MSDS is essential before use.

 

Frequently Asked Questions (FAQs)

  1. Is Adapalene safe for topical use?

    Yes, Adapalene is widely used in dermatology and cosmetic formulations for acne treatment with low irritation potential.

  2. What is Adapalene used for?

    It is used in pharmaceutical and cosmetic products to treat acne, improve skin texture, and reduce blemishes.

  3. Can Adapalene be combined with other active ingredients?

    Yes, it is often formulated with Benzoyl Peroxide, Clindamycin, or Salicylic Acid for enhanced acne treatment.

  4. Is Adapalene stable for long-term formulations?

    Yes, it is photostable and maintains effectiveness in gels, creams, and lotions under proper storage conditions.

  5. What grades of Adapalene are available?

    ChemicalBull supplies pharmaceutical-grade, dermatology-grade, and cosmetic-grade Adapalene depending on customer requirements.