5-Iodo-2-Methylbenzoic Acid | 54811-38-0

Description :

Overview of 5-Iodo-2-Methylbenzoic Acid

5-Iodo-2-Methylbenzoic Acid (CAS: 54811-38-0) is a halogenated aromatic carboxylic acid widely used as a pharmaceutical intermediate, agrochemical building block, and specialty organic synthesis reagent. It typically appears as a white to light yellow crystalline powder and contains both iodine and carboxylic functional groups, which make it highly useful in advanced organic chemistry reactions.

This compound is commonly applied in drug discovery, medicinal chemistry, and fine chemical manufacturing, where halogenated aromatic acids are required as key intermediates. The iodine substituent allows efficient cross-coupling reactions such as Suzuki, Sonogashira, and Heck reactions, making it valuable in modern synthetic chemistry.

In halogenated aromatic intermediate chemistry, compounds such as 2-Iodobenzoic Acid, 4-Iodotoluene, and 2-Bromobenzoic Acid are also widely used for pharmaceutical synthesis, agrochemical intermediates, and specialty organic transformations.

Applications of 5-Iodo-2-Methylbenzoic Acid

Pharmaceutical Intermediates

5-Iodo-2-Methylbenzoic Acid plays an important role in API and medicinal compound synthesis.

• Used as a building block in pharmaceutical intermediates

• Supports synthesis of iodinated aromatic drug molecules

• Suitable for cross-coupling reactions in drug discovery

• Used in research involving halogenated bioactive compounds

Agrochemical Manufacturing

This compound is useful in agrochemical intermediate production.

• Used in synthesis of herbicides and pesticide intermediates

• Helps produce iodinated aromatic agro compounds

• Applied in crop-protection chemical development

Specialty Chemical Manufacturing

5-Iodo-2-Methylbenzoic Acid is used in fine chemical synthesis and industrial intermediates.

• Applied in custom organic synthesis

• Used to manufacture specialty aromatic intermediates

• Supports iodine-based substitution and coupling reactions

• Used in high-value chemical production

Organic Synthesis & Catalytic Chemistry

The compound is widely used in advanced organic reactions.

• Suitable for Suzuki and palladium-catalyzed coupling reactions

• Used in aryl-iodide based transformations

• Applied in functional aromatic compound synthesis

Research & Laboratory Applications

Used extensively in academic and industrial R&D laboratories.

• Used in medicinal chemistry research

• Supports synthetic methodology development

• Useful in iodinated aromatic compound studies

Safety & Handling Guidelines

• Avoid contact with skin, eyes, and clothing

• Use protective gloves, goggles, and lab safety equipment

• Handle in well-ventilated laboratory or industrial areas

• Store in tightly sealed containers away from moisture

• Keep away from strong oxidizing agents

• Follow COA and MSDS instructions carefully

Where to Buy 5-Iodo-2-Methylbenzoic Acid?

5-Iodo-2-Methylbenzoic Acid Manufacturer

ChemicalBull supplies high-purity 5-Iodo-2-Methylbenzoic Acid suitable for pharmaceutical intermediates, agrochemical synthesis, and specialty organic manufacturing.

5-Iodo-2-Methylbenzoic Acid Supplier & Distributor

• Available in laboratory and industrial bulk packaging

• Suitable for organic synthesis and R&D applications

• COA, MSDS, and detailed technical specifications available

5-Iodo-2-Methylbenzoic Acid MSDS

• May cause irritation to skin, eyes, and respiratory tract

• Avoid inhalation of dust particles

• Use protective equipment when handling

• Store in cool, dry, well-ventilated environments

• Refer to the complete MSDS for spill control and emergency response

Frequently Asked Questions (FAQs)

1. What is the molecular formula of 5-Iodo-2-Methylbenzoic Acid?

   Molecular Formula: C₈H₇IO₂
   Molecular Weight: 262.04 g/mol
   
   

2. What is 5-Iodo-2-Methylbenzoic Acid used for?

   It is mainly used as a pharmaceutical intermediate, agrochemical building block, and reagent for cross-coupling reactions in organic synthesis.
   
   

3. Why is iodine used in aromatic intermediates?

   Iodine substituents make aromatic compounds highly reactive in palladium-catalyzed coupling reactions, which are widely used in drug and specialty chemical synthesis.
   
   

4. Which industries use 5-Iodo-2-Methylbenzoic Acid?

   Industries include pharmaceutical manufacturing, agrochemical development, fine chemical production, and research laboratories.
   
   

5. Is 5-Iodo-2-Methylbenzoic Acid hazardous?

   It may cause skin, eye, or respiratory irritation, so proper PPE and safe handling procedures should always be followed.