4-Methoxyphenylacetonitrile | 104-47-2

Cas No :

104-47-2

Form :

Liquid

Molecular Weight :

147.17 G/Mol

Molecular Formula :

147.17 G/MOL

Boiling Point :

235 °C

Melting Point :

-14 °Cn/A

Flash Point :

95 °C

Solubility :

Slightly Soluble In Water; Soluble In Organic Solvents (Acetone, Chloroform, Dichloromethane)

Description :

Overview of 4-Methoxyphenylacetonitrile

4-Methoxyphenylacetonitrile is an important aromatic nitrile intermediate widely used in pharmaceutical synthesis, fragrance intermediates, agrochemical actives, and fine chemical manufacturing. The combination of a para-methoxy group and a reactive acetonitrile side chain makes it suitable for condensation, reduction, and substitution reactions in industrial synthesis.

On ChemicalBull, several related chemical intermediates—such as 3-Chloroanisole, 1,4-Benzoquinone, 1,3-Dichloropropane, and 2,3,4-Trimethoxybenzaldehyde


Applications of 4-Methoxyphenylacetonitrile

Pharmaceutical Intermediate

  • Used in the production of API intermediates and specialty molecules

  • Participates in Grignard reactions, reductive transformations, and condensation steps

  • Common in CNS, anti-inflammatory, and metabolic research molecules


Agrochemical Synthesis

  • Serves as a precursor for herbicides, plant growth regulators, and controlled-release compounds

  • Offers excellent stability during complex synthesis reactions


Fragrance & Aroma Chemical Intermediate

  • Used to prepare aromatic esters and aldehydes

  • Valuable for developing musky, floral, and fruity scent molecules


Fine & Specialty Chemicals

  • Suitable for developing custom synthesis molecules

  • Used in dye intermediates, polymer additives, and R&D formulations


Organic Synthesis

  • Highly versatile for:

    • Substitution reactions

    • Reduction to amines

    • Hydrolysis to acids

    • Building block for heterocycles


Safety & Handling Guidelines

  • Avoid inhalation of vapors or dust

  • Use protective gloves, goggles, and lab coat

  • Store in a tightly sealed container in a cool, dry place

  • Keep away from oxidizing agents and heat sources

  • Refer to MSDS for full hazard details


Where to Buy 4-Methoxyphenylacetonitrile?

4-Methoxyphenylacetonitrile Manufacturer

Produced in high purity suitable for pharmaceutical and organic synthesis applications.


4-Methoxyphenylacetonitrile Supplier & Exporter

ChemicalBull supplies:

  • Bulk & commercial packaging options

  • COA, MSDS & stringent purity compliance

  • Export-grade packing and global dispatch support


4-Methoxyphenylacetonitrile MSDS 

  • Physical & chemical properties

  • Hazards & PPE

  • Safe handling and storage

  • Emergency & transportation guidelines

 

Frequently Asked Questions (FAQs)

  1. What is 4-Methoxyphenylacetonitrile used for?

    It is mainly used as an intermediate in pharmaceutical, agrochemical, fragrance, and fine chemical synthesis.

  2. Is it suitable for API manufacturing?

    Yes, it is commonly used in multi-step API intermediate production.

  3. Do you provide bulk industrial-grade supply?

    Yes, ChemicalBull supplies bulk and export quantities with full documentation.

  4. Can it be reduced to produce amine derivatives?

    Yes, it undergoes reductive amination and catalytic hydrogenation to form valuable amines.

  5. Do you provide COA & MSDS?

    Yes, both documents are supplied with every batch.