1,3-difluorobenzene | 372-18-9
Cas No :
372-18-9
Synonyms :
Form :
Liquid
Molecular Weight :
114.094 G/mol
Molecular Formula :
C6H4F2
Boiling Point :
104 °c
Melting Point :
-9 °c
Flash Point :
-20 °c
Solubility :
Soluble In Organic Solvents; Insoluble In Water
Description :
Overview of 1,3-Difluorobenzene
1,3-Difluorobenzene is a highly demanded fluorinated aromatic intermediate used across pharmaceuticals, agrochemicals, and advanced material synthesis. Its two fluorine substituents positioned meta on the benzene ring make it a valuable raw material for aromatic substitution, coupling reactions, polymer applications, and fluorine-based drug intermediates.
On ChemicalBull, similar products such as 1,2-Difluorobenzene, 1,4-Difluorobenzene, 1-Fluoro-3-nitrobenzene, 1-Chloro-4-fluorobenzene .
Applications of 1,3-Difluorobenzene
Pharmaceutical Intermediates
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Used to develop fluorinated APIs
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Supports synthesis requiring aromatic fluorination
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Useful in medicinal chemistry for enhancing drug bioavailability
Agrochemical Manufacturing
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Applied in herbicide and pesticide intermediate development
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Provides stability and reactivity to advanced agro formulations
Specialty Chemicals & Polymers
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Used in high-performance materials and fluorinated polymers
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Supports electronic chemical manufacturing
Organic Synthesis
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Participates in cross-coupling reactions like Suzuki & Buchwald
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Ideal for nucleophilic aromatic substitution (SNAr) pathways
Research & Laboratory Applications
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Valuable reagent in advanced aromatic studies
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Commonly used in reaction mechanism research
Safety & Handling Guidelines
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Store in a cool, dry, ventilated area
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Keep away from strong oxidizing agents
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Avoid direct contact and inhalation
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Use gloves, goggles, and mask
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Dispose of material according to MSDS guidelines
Where to Buy 1,3-Difluorobenzene?
1,3-Difluorobenzene Manufacturer
Produced under strict purity standards suitable for industrial and research-grade applications.
1,3-Difluorobenzene Supplier & Exporter
ChemicalBull offers high-quality 1,3-Difluorobenzene with COA, MSDS, and export-safe packaging.
MSDS for 1,3-Difluorobenzene
Includes hazard profile, safe handling, first-aid, reactivity data, and storage recommendations.
Frequently Asked Questions (FAQs)
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What is 1,3-Difluorobenzene used for?
It is widely used in pharmaceuticals, agrochemicals, and fluorinated specialty chemical synthesis. -
Is it an important fluorinated intermediate?
Yes, its meta-fluorinated structure is crucial for aromatic substitution and coupling chemistry. -
Do you provide bulk quantities?
Yes, ChemicalBull supplies industrial and export-grade bulk quantities with certification. -
Is 1,3-Difluorobenzene hazardous?
It should be handled with PPE and stored properly; refer to MSDS for safety instructions. -
Can it be used in research applications?
Yes, it is frequently used in SNAr reactions, cross-coupling, and aromatic chemistry studies.
ChemicalBull supplies 1,3-difluorobenzene across India, serving customers in Andhra Pradesh, Arunachal Pradesh, Assam, Bihar, Chhattisgarh, Goa, Gujarat, Haryana, Himachal Pradesh, Jharkhand, Karnataka, Kerala, Madhya Pradesh, Maharashtra, Manipur, Meghalaya, Mizoram, Nagaland, Odisha, Punjab, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Uttar Pradesh, Uttarakhand, and West Bengal, as well as the Union Territories of Andaman & Nicobar Islands, Chandigarh, Dadra & Nagar Haveli and Daman & Diu, Delhi, Jammu & Kashmir, Ladakh, Lakshadweep, and Puducherry. We serve pharmaceutical, chemical, research, academic, laboratory, manufacturing, and industrial customers with reliable nationwide delivery.