1,3-Difluorobenzene | 372-18-9

Description :

Overview of 1,3-Difluorobenzene

1,3-Difluorobenzene is a highly demanded fluorinated aromatic intermediate used across pharmaceuticals, agrochemicals, and advanced material synthesis. Its two fluorine substituents positioned meta on the benzene ring make it a valuable raw material for aromatic substitution, coupling reactions, polymer applications, and fluorine-based drug intermediates.

On ChemicalBull, similar products such as 1,2-Difluorobenzene, 1,4-Difluorobenzene, 1-Fluoro-3-nitrobenzene, 1-Chloro-4-fluorobenzene .

Applications of 1,3-Difluorobenzene

Pharmaceutical Intermediates

• Used to develop fluorinated APIs

• Supports synthesis requiring aromatic fluorination

• Useful in medicinal chemistry for enhancing drug bioavailability

Agrochemical Manufacturing

• Applied in herbicide and pesticide intermediate development

• Provides stability and reactivity to advanced agro formulations

Specialty Chemicals & Polymers

• Used in high-performance materials and fluorinated polymers

• Supports electronic chemical manufacturing

Organic Synthesis

• Participates in cross-coupling reactions like Suzuki & Buchwald

• Ideal for nucleophilic aromatic substitution (SNAr) pathways

Research & Laboratory Applications

• Valuable reagent in advanced aromatic studies

• Commonly used in reaction mechanism research

Safety & Handling Guidelines

• Store in a cool, dry, ventilated area

• Keep away from strong oxidizing agents

• Avoid direct contact and inhalation

• Use gloves, goggles, and mask

• Dispose of material according to MSDS guidelines

Where to Buy 1,3-Difluorobenzene?

1,3-Difluorobenzene Manufacturer

Produced under strict purity standards suitable for industrial and research-grade applications.

1,3-Difluorobenzene Supplier & Exporter

ChemicalBull offers high-quality 1,3-Difluorobenzene with COA, MSDS, and export-safe packaging.

MSDS for 1,3-Difluorobenzene

Includes hazard profile, safe handling, first-aid, reactivity data, and storage recommendations.

Frequently Asked Questions (FAQs)

1. What is 1,3-Difluorobenzene used for?

   It is widely used in pharmaceuticals, agrochemicals, and fluorinated specialty chemical synthesis.
   
   

2. Is it an important fluorinated intermediate?

   Yes, its meta-fluorinated structure is crucial for aromatic substitution and coupling chemistry.
   
   

3. Do you provide bulk quantities?

   Yes, ChemicalBull supplies industrial and export-grade bulk quantities with certification.
   
   

4. Is 1,3-Difluorobenzene hazardous?

   It should be handled with PPE and stored properly; refer to MSDS for safety instructions.
   
   

5. Can it be used in research applications?

   Yes, it is frequently used in SNAr reactions, cross-coupling, and aromatic chemistry studies.