1,1,1-Trifluoro-2-Propanone

Description :

Overview of 1,1,1-Trifluoro-2-Propanone

1,1,1-Trifluoro-2-Propanone (CAS: 421-50-1) is a highly reactive fluorinated ketone widely used in pharmaceutical intermediates, agrochemical synthesis, polymer chemistry, and speciality chemical manufacturing.

It appears as a clear, volatile liquid and is known for its strong electrophilic nature due to the presence of trifluoromethyl and carbonyl functional groups.

This compound is an important industrial building block used in fluorinated compound synthesis, halogenated intermediates, and fine chemical production. Its reactivity makes it valuable in Grignard reactions, coupling reactions, condensation processes, and advanced organic transformations.

Related products available on ChemicalBull: Trifluoroacetic Acid, Trifluoroethanol, Trifluoromethyl Iodide – commonly used in fluorinated intermediates and speciality chemical applications.

 

Applications of 1,1,1-Trifluoro-2-Propanone

Pharmaceutical Intermediates

  • Widely used for synthesising fluorinated drug intermediates
  • Supports the development of APIs requiring CF₃-functionalized aromatic and aliphatic compounds
  • Suitable for nucleophilic addition, reduction, and condensation reactions

Agrochemical Synthesis

  • Used to produce high-performance pesticides and herbicide intermediates
  • Helps develop fluorinated agrochemical actives with enhanced stability and activity

Polymer & Material Chemistry

  • Applied in manufacturing speciality polymers and fluorinated materials
  • Useful in producing advanced coatings, adhesives, and high-performance materials
  • Participates in polymer modification and cross-linking reactions

Speciality Chemical Manufacturing

  • Key reagent for fluorination chemistry
  • Used in producing fine chemicals and halogenated intermediates
  • Suitable for large-scale industrial organic synthesis

Laboratory & Research Applications

  • Used in R&D labs for complex organic synthesis
  • Ideal for developing fluorinated analogues of industrial chemicals
  • Supports research in drug discovery and fluorine chemistry

 

Safety & Handling Guidelines

  • Avoid inhalation and skin/eye contact
  • Use gloves, goggles, and protective clothing
  • Ensure handling in a fume hood due to high volatility
  • Store in airtight containers in a cool, dry place
  • Follow COA and MSDS instructions

 

MSDS Highlights

  • Refer to the full MSDS for emergency procedures.

 

Where to Buy 1,1,1-Trifluoro-2-Propanone?

1,1,1-Trifluoro-2-Propanone Manufacturer

ChemicalBull supplies high-purity 1,1,1-Trifluoro-2-Propanone for pharmaceuticals, agrochemicals, polymers, and industrial chemical applications.

1,1,1-Trifluoro-2-Propanone Supplier & Distributor

  • Available in laboratory and bulk quantities
  • Suitable for fluorination, intermediates production, and fine chemical synthesis
  • COA, MSDS, and technical specifications provided

 

Frequently Asked Questions (FAQs)

What is the molecular formula of 1,1,1-Trifluoro-2-Propanone?

Molecular Formula: C₃H₃F₃O

Molecular Weight: 116.05 g/mol

What is 1,1,1-Trifluoro-2-Propanone used for?

Used in pharmaceutical synthesis, agrochemical intermediates, fluorinated material development, and advanced organic reactions.

Is 1,1,1-Trifluoro-2-Propanone hazardous?

Yes, it is volatile and flammable; vapours may irritate. Handle with PPE and follow MSDS guidelines.