Trimethylsulfoxonium Iodide | 1774-47-6

Description :

Overview of Trimethylsulfoxonium Iodide

Trimethylsulfoxonium Iodide is a sulfur ylide precursor used extensively in organic synthesis for epoxidation reactions and cyclopropanation. Known for its use in the Corey-Chaykovsky reaction to convert carbonyl compounds to epoxides and for its mild reaction conditions, Trimethylsulfoxonium Iodide is widely used in pharmaceutical synthesis, natural product chemistry, and fine chemical manufacturing.

This compound appears as a white to off-white crystalline powder. Its sulfoxonium structure enables the generation of sulfur ylides under basic conditions for various carbon-carbon bond-forming reactions.

Related products include Trimethylsulfonium Iodide, Trimethylsulphonium Bromide, Dimethylsulfoxonium Methylide, and other ylide precursors used in organic synthesis.

Applications of Trimethylsulfoxonium Iodide

Pharmaceutical Synthesis

• It is used in Corey-Chaykovsky's electrochemical reactions
• Utilized in the production of Epoxide intermediates to aid in chemical synthesis
• It is used for the cyclopropanation process of activated alkenes
• It is used to synthesize pharmaceutical intermediates

Industrial Organic Synthesis

• It is used in the preparation of the building blocks of epoxide
• Utilized in the overall synthesis of natural products
• It is used to synthesize the cyclopropane derivatives
• Applied in developing synthetic methodologies
• It is used in an asymmetric synthesizer software
• It is used in the field of material Chemistry
• It is used in special chemical production
• Utilized in an agrochemical intermediate synthesis

Research Applications

• Used in academic and industrial research
• Applied in method development
• Used in studying reaction mechanisms
• Applied in synthetic organic chemistry
• Used in chemical biology applications
• Applied in drug discovery programs

Safety & Handling Guidelines

• Avoid inhalation of dust
• Use gloves, goggles, and protective clothing
• Handle in well-ventilated areas
• Store in tightly closed containers in a cool, dry place
• Keep away from strong acids and oxidizing agents
• Hygroscopic—protect from moisture
• Follow COA and MSDS instructions strictly

Where to Buy Trimethylsulfoxonium Iodide?

Trimethylsulfoxonium Iodide Manufacturer

ChemicalBull supplies high-purity Trimethylsulfoxonium Iodide, meeting pharmaceutical and research quality standards.

Trimethylsulfoxonium Iodide Supplier & Distributor

• Available in bulk quantities for pharmaceutical and research use
• High-purity grades (98%, 99%)
• Pharmaceutical and research grades
• COA, MSDS, and specifications provided

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is Trimethylsulfoxonium Iodide used for?
   

   Used in Corey-Chaykovsky epoxidation to convert aldehydes/ketones to epoxides, cyclopropanation reactions, and pharmaceutical intermediate synthesis.
   
   

2. What is the molecular formula?
   

   Molecular formula: C₃H₉IOS with molecular weight 220.07 g/mol.
   
   

3. How does the Corey-Chaykovsky reaction work?
   

   Base deprotonates trimethylsulfoxonium iodide, generating a ylide which reacts with a carbonyl compound, forming an epoxide with the loss of dimethyl sulfoxide.