Trimethylsilyl Polyphosphate | 40623-46-9

Cas No :

40623-46-9

Form :

Powder 

Molecular Weight :

410.25 G/Mol

Boiling Point :

250 °C

Melting Point :

110 °C

Flash Point :

220 °C

Solubility :

Insoluble In Water; Soluble In Acetone And Acetonitrile

Description :

Overview of Trimethylsilyl Polyphosphate

Trimethylsilyl Polyphosphate (TMSP) is a highly reactive organophosphorus compound widely used as a phosphorylating and dehydrating reagent in advanced organic synthesis. It belongs to the class of silylated polyphosphates and is valued for its ability to introduce phosphate groups into organic molecules under controlled conditions. Due to its strong reactivity and efficient phosphorylation capability, Trimethylsilyl Polyphosphate is frequently used in pharmaceutical, biochemical, and specialty chemical manufacturing.


Applications of Trimethylsilyl Polyphosphate

Pharmaceutical & Nucleotide Synthesis

Trimethylsilyl Polyphosphate is widely used in the synthesis of nucleotides and phosphorylated intermediates. It enables efficient phosphorylation reactions used in pharmaceutical research and biochemical applications.

It may be used in reaction systems involving Triethylamine and Phosphorus Oxychloride for controlled phosphorylation processes.

Organic Synthesis & Phosphorylation Reactions

In organic chemistry, Trimethylsilyl Polyphosphate functions as a powerful phosphorylating agent for converting alcohols and other functional groups into phosphate esters. This makes it useful in advanced synthetic routes for complex organic molecules.

Biochemical & Research Applications

The compound is widely used in biochemical research laboratories for studying phosphorylation mechanisms and preparing phosphate-containing biomolecules.

Specialty Chemical Manufacturing

Trimethylsilyl Polyphosphate is used in the production of specialty chemical intermediates where phosphate incorporation is required to improve molecular functionality and reactivity.


Safety & Handling Guidelines

  • Store in tightly sealed containers in a cool, dry environment

  • Protect from moisture and humidity

  • Avoid inhalation of vapors and direct skin contact

  • Use protective gloves, goggles, and laboratory protective clothing

  • Handle under a chemical fume hood with proper ventilation

  • Dispose of material according to hazardous waste regulations

Always consult the official MSDS before handling.


Where to Buy Trimethylsilyl Polyphosphate?

Trimethylsilyl Polyphosphate Manufacturer

Trimethylsilyl Polyphosphate is manufactured under controlled chemical synthesis conditions to ensure high purity, stable composition, and reliable performance in advanced organic reactions.

Trimethylsilyl Polyphosphate Supplier & Distributor

Buy Trimethylsilyl Polyphosphate from Chemicalbull Pvt. Ltd., a trusted industrial chemical supplier and distributor in India offering reliable bulk supply and compliant logistics support.

For the latest pricing and bulk supply information, contact Chemicalbull Pvt. Ltd. for a competitive industrial quotation.


MSDS for Trimethylsilyl Polyphosphate

The MSDS for Trimethylsilyl Polyphosphate provides detailed information on hazard identification, safe handling procedures, storage requirements, exposure controls, and emergency response measures. Industrial and laboratory users should review the safety data sheet before use.


Frequently Asked Questions (FAQs)

  1. What is Trimethylsilyl Polyphosphate?

    Trimethylsilyl Polyphosphate is a phosphorylating reagent used in organic synthesis and nucleotide preparation.

  2. What is the Trimethylsilyl polyphosphate formula?

    It is generally represented as [(CH₃)₃SiO]ₙPO₃, indicating a silylated polyphosphate structure.

  3. What is the Trimethylsilyl polyphosphate structure?

    It consists of polyphosphate chains linked with trimethylsilyl groups that enhance its solubility and reactivity in organic reactions.