Triethyl Orthoformate | 122-51-0

Cas No :

122-51-0

Form :

Liquid

Molecular Weight :

148.2

Molecular Formula :

C7H16O3

Melting Point :

76 °C

Boiling Point :

145 °C

Solubility :

Chlorofor, Ethyl Acetate, Methanol

Description :

Triethyl Orthoformate Overview

 

Triethyl Orthoformate, a colorless to light yellow organic compound commonly utilized as a formylating chemical, a group-protecting reagent, and an intermediate in pharmaceutical as well as chemical syntheses. It's a triester of orthoformic acid, and is a key component in organic chemistry reactions, specifically when it comes to the creation of ethers, esters, and heterocyclic compounds.

It is frequently utilized in conjunction with sulfur-containing substances like Thiophenol and Thiourea in specific organic synthesis.

Chemical Formula: C7H16O3 or HC(OC2H5)3

The structure: Central carbon atom that is bonded with three groups of ethoxy

Reactivity: Very reactive with acid and water, it is useful in dehydration reactions as well for water removal in chemical processes.

 

 

Application of triethyl Orthoformate

 

Pharmaceutical & Chemical Synthesis

 

  • It is used to serve as an agent for mylating to aid in the process of drug synthesis.
  • Secures the carbonyl as well as functional groups, hydroxyl 
  • An essential intermediate to the creation of homocyclic compounds
  • Helps facilitate the esterification process and reactions to etherification

 

Industrial & Specialty Applications

 

  • It is a water dehydrating ingredient during the chemical process
  • It is used for fragrance and the synthesis of fragrances
  • Used in the production of agrochemicals
  • Used for polymer as well as resin manufacturing

 

 

Safety and Handling Instructions

 

  • Always use eye protection or gloves, as well as protective clothes
  • Beware of any contact with the water acid, water, or other oxidizing agents
  • Use only in an area that is well ventilated.
  • Store in sealed containers
  • Use MSDS and other safety protocols

 

 

Where to Buy Triethyl Orthoformate

 

Triethyl Orthoformate Manufacturer

 

  • ChemicalBull supplies high-quality Triethyl Orthoformate
  • Suitable for pharmaceutical synthesis, chemical manufacturing, and industrial applications

 

Triethyl Orthoformate Supplier & Distributor

 

  • Bulk and export-grade supply
  • COA, TDS & MSDS available
  • Reliable delivery for industrial users

 

 

Triethyl Orthoformate MSDS

 

Includes information on hazards, handling, storage, and emergency precautions

 

 

Frequently Asked Questions (FAQs)

 

1. What is the Triethyl Orthoformate CAS No?

The CAS number is 122-51-0

 

2. How is Triethyl Orthoformate synthesized?

Synthesized through the reaction of chloroform with sodium ethoxide Or by reacting orthoformic acid with ethanol

 

3. What is the Triethyl Orthoformate mechanism?

Acts as an acetal-forming reagent or Reacts with nucleophiles and undergoes acid-catalyzed transesterification reactions