Tert-Butyl Bromoacetate | 5292-43-3

Cas No :

5292-43-3

Form :

Liquid

Molecular Weight :

195.06 G/Mol

Molecular Formula :

C6H11BRO2

Boiling Point :

152 °C

Melting Point :

-25 °C

Flash Point :

25 °C

Solubility :

Practically Insoluble In Water; Soluble In Organic Solvents Such As Acetone And Dichloromethane

Description :

Overview of Tert-Butyl Bromoacetate

Tert-Butyl Bromoacetate is a high-quality pharmaceutical alkylating reagent that is widely employed to create organic compounds as well as API development. It functions as a secured ester derivative that allows controlled functional group transformations in multi-step pharmaceutical syntheses.

In pharmaceutical manufacturing, Tert-Butyl Bromoacetate is valued for its reactivity, stability under controlled conditions, and efficiency in esterification and substitution reactions. It is produced under regulated conditions to ensure high purity and consistent batch performance. Tert-butyl bromoacetate manufacturers in India supply this compound for both domestic and export-oriented pharmaceutical industries.

As a pharma chemical, Tert-Butyl Bromoacetate functions primarily as a synthetic intermediate rather than a therapeutic ingredient.


Applications of Tert-Butyl Bromoacetate

API Intermediate Development

Tert-Butyl Bromoacetate is widely used in the synthesis of active pharmaceutical ingredients where ester protection and controlled alkylation are required. It allows chemists to introduce tert-butyl ester groups that can later be selectively removed during final API processing.

Peptide & Specialty Molecule Synthesis

In pharmaceutical R&D as well as commercial manufacturing, Tert-Butyl Bromoacetate is utilized for the production of amino acid derivatives as well as the peptide intermediates. Its controlled reactivity allows for exact molecular modifications of the most valuable drug candidates.

Protective Group Chemistry & Process Optimisation

Tert-Butyl Bromoacetate plays a crucial function in protecting group strategies in multi-step pharmaceutical syntheses. It increases the efficiency of reaction selection and improves the scalability of GMP-compliant manufacturing facilities.

Industrial Pharmaceutical Synthesis

Tert-Butyl Bromoacetate is used in large-scale chemical manufacturing processes that require ester-functional intermediatesIt helps to ensure the efficient carbon-carbon bond and carbon-heteroatom formation in pharmaceutical production that is controlled.

In advanced intermediate portfolios, it is often evaluated alongside Di-Tert-Butyl Dicarbonate, N, N-Dicyclohexylcarbodiimide, and Triphosgene for complex API synthesis planning.


Safety & Handling Guidelines

  • Store in a cool, dry, and well-ventilated area
  • Protect from moisture and excessive heat
  • Keep containers tightly sealed and clearly labelled
  • Beware of inhalation or direct contact with the substance.
  • Wear chemical-resistant personal protective equipment
  • Controlled pharmaceutical manufacturing conditions
  • The disposal of waste should be in accordance with the regulations for hazardous chemicals


Where to Buy Tert-Butyl Bromoacetate?

Tert-Butyl Bromoacetate Manufacturer

Tert-Butyl bromoacetate is used in pharmaceutical synthesis where controlled purity, consistency in reactivity, and regulatory compliance are vital.

Tert-Butyl Bromoacetate Supplier & Distributor

Pharmaceutical-grade Tert-Butyl Bromoacetate is supplied in industrial packaging for API manufacturers and research laboratories. As a pharmaceutical chemicals supplier and distributor, Chemicalbull Pvt. Ltd. supports reliable sourcing with standard documentation.


MSDS for Tert-Butyl Bromoacetate

The MSDS for Tert-Butyl Bromoacetate provides detailed information about the dangers and safe handling procedures, the requirements for storage, exposure control, and emergency response protocols. It is required to be reviewed prior to use in industrial or laboratory environments.


Frequently Asked Questions (FAQs)

  1. What is Tert-Butyl Bromoacetate used for?

    Tert-Butyl Bromoacetate is used in pharmaceutical synthesis as an intermediate for ester formation and controlled alkylation reactions.

  2. What is the structure of Tert-Butyl Bromoacetate?

    Tert-butyl bromoacetate structure consists of a tert-butyl ester group attached to a bromoacetyl moiety.

  3. Are there Tert-Butyl Bromoacetate manufacturers in India?

    Yes, Tert-butyl bromoacetate manufacturer in India, Chemicalbull supplies pharmaceutical-grade material for regulated synthesis applications.

  4. Is Tert-Butyl Bromoacetate an API?

    No, it is primarily used as a pharmaceutical intermediate in drug synthesis.

  5. Is Tert-Butyl Bromoacetate suitable for GMP manufacturing?

    Yes, pharmaceutical-grade material is produced for controlled and regulated pharmaceutical production environments.