Tenofovir Disoproxil Fumarate | 202138-50-9
Cas No :
202138-50-9
Form :
Powder
Molecular Weight :
635.54 G/Mol
Molecular Formula :
C15H26O6
Boiling Point :
270 °C
Melting Point :
125 °C
Flash Point :
170 °C
Solubility :
Soluble In Water
Description :
Overview of Tenofovir Disoproxil Fumarate
Tenofovir Disoproxil Fumarate can be described as a pharmaceutical-grade antiviral drug ingredient that is widely used in treating viral diseases, specifically HIV and Hepatitis B. It is a protodrug formulation that is designed to increase oral bioavailability and stability as compared to the main compound.
In pharmaceutical manufacturing, Tenofovir Disoproxil Fumarate is valued for its well-established antiviral efficacy, formulation compatibility, and suitability for large-scale global production. It is produced under strict GMP-compliant conditions to meet pharmacopeial standards for purity, assay, and impurity control.
As a pharma chemical, Tenofovir Disoproxil Fumarate plays a central role in antiviral therapy development and combination drug manufacturing.
Applications of Tenofovir Disoproxil Fumarate
Antiretroviral Therapy (ART) Formulation Development
Tenofovir Disoproxil Fumarate is commonly utilized in oral tablet formulations designed to aid in HIV cure and prevention. It is integrated into fixed-dose combinations as a part of traditional antiretroviral therapy regimens.
Hepatitis B Treatment Products
Tenofovir Disoproxil Fumarate is used in pharmaceutical formulations targeting chronic hepatitis B infection. Its antiviral activity supports long-term viral suppression strategies in regulated therapeutic products.
Fixed-Dose Combination Manufacturing
Tenofovir Disoproxil Fumarate can typically be mixed along with various antiviral APIs within single-tablet regimens. Its compatibility with many drugs makes it suitable for the development of combination therapies in controlled manufacturing conditions.
Large-Scale GMP Antiviral Production
Tenofovir Disoproxil Fumarate synthesis is carried out under strict pharmaceutical manufacturing conditions that guarantee consistency in purity and performance. It enables scalable production for global health initiatives.
In antiviral portfolios, it is often evaluated alongside Lamivudine, Emtricitabine, and Efavirenz for therapeutic optimisation and combination development.
Safety & Handling Guidelines
- Keep it in a cool, humid, dry, and well-controlled space
- Beware of moisture and extreme heat.
- Seal containers well and keep them clearly labeled
- Beware of inhaling powders when handling
- Use appropriate personal protective equipment
- Handle under controlled pharmaceutical manufacturing conditions
- Dispose of waste according to regulatory guidelines
Where to Buy Tenofovir Disoproxil Fumarate?
Tenofovir Disoproxil Fumarate Manufacturer
Tenofovir Disoproxil Fumarate is manufactured for pharmaceutical antiviral applications where controlled potency, consistent quality, and regulatory compliance are essential.
Tenofovir Disoproxil Fumarate Supplier & Distributor
Pharmaceutical-grade Tenofovir Disoproxil Fumarate is supplied in suitable packaging for formulation manufacturers. As a pharmaceutical chemicals supplier and distributor, Chemicalbull Pvt. Ltd. supports reliable sourcing with standard documentation.
MSDS for Tenofovir Disoproxil Fumarate
The MSDS for Tenofovir Disoproxil provides comprehensive information about the risks, as well as safe handling practices, storage conditions, exposure control, and emergency response protocols. It should be reviewed prior to using the pharmaceutical manufacturing.
Frequently Asked Questions (FAQs)
-
What is Tenofovir Disoproxil Fumarate used for?
Tenofovir Disoproxil Fumarate is used in pharmaceutical formulations for the treatment and prevention of HIV infection and for the treatment of chronic hepatitis B. -
What are the side effects of Tenofovir Disoproxil Fumarate?
Tenofovir disoproxil fumarate side effects may include gastrointestinal discomfort, renal effects, and changes in bone mineral density, depending on dosage and duration. -
What is the solubility of Tenofovir Disoproxil Fumarate?
Tenofovir disoproxil fumarate solubility supports oral dosage form development through controlled pharmaceutical formulation techniques. -
What is the difference between tenofovir and tenofovir disoproxil fumarate?
Tenofovir disoproxil fumarate is a prodrug form designed to improve oral absorption, whereas tenofovir refers to the active antiviral compound. -
Is Tenofovir Disoproxil Fumarate suitable for combination therapy?
Yes, it is widely used in fixed-dose combination antiretroviral products.