Sugammadex Sodium | 343306-79-6

Description :

Overview of Sugammadex Sodium

Sugammadex, the sodium compound, is a modified derivative of gamma-cyclodextrin, which is a selective relaxation binding agent to reverse neural blockade caused by rocuronium as well as vecuronium.

Known for its rapid and complete reversal of neuromuscular blockade through an encapsulation mechanism, Sugammadex Sodium is widely used in anesthesiology for managing post-surgical muscle relaxation and emergency reversal situations.

This API appears as a white to off-white powder with excellent water solubility. Its mechanism—forming tight 1:1 complexes with aminosteroid neuromuscular blocking agents through molecular encapsulation—rapidly reduces free plasma concentrations of these agents, allowing neuromuscular function recovery without the limitations of traditional anticholinesterase reversal agents.

Related products include Neostigmine, Pyridostigmine, and other neuromuscular blockade reversal agents used in anesthetic management.

Applications of Sugammadex Sodium

Pharmaceutical API

• Used for the reversal of rocuronium-induced neuromuscular blockade
• Applied for the reversal of vecuronium-induced muscle relaxation
• Effective in immediate reversal situations (cannot intubate/cannot ventilate)
• Used across all depths of blockade (shallow, moderate, deep)
• Applied in routine anesthesia recovery
• Emergency reversal in difficult airway situations

Formulation Development

• Used in an injectable solution for intravenous administration
• Single-dose vials in various strengths
• Rapid preparation and administration
• Stable in solution form
• Requires specific storage conditions
• Compatible with standard IV administration

Anesthetic Management

• Allows for rapid reverse within 2 to 3 minutes
• more reliable than anticholinesterase drugs
• No muscarinic side effects (unlike neostigmine)
• Can reverse deep blockade
• Lowers the time needed for anesthesia and the time spent in the recovery room
• Improves patient safety in emergency situations

Safety & Handling Guidelines

• Beware of inhaling fine powder
• Make sure you wear gloves, goggles, or appropriate clothing when handling
• Store as per specifications from the manufacturer
• Be safe from the light
• Use the COA as well as the MSDS directions completely

Where can I buy Sugammadex Sodium?

Sugammadex Sodium Manufacturer

ChemicalBull offers the highest purity Sugammadex Sodium API, meeting USP and IP/EP quality standards for formulations used in pharmaceuticals.

Sugammadex Sodium Supplier & Distributor

• Bulk packaging is available to facilitate pharmaceutical manufacturing
• Grade of high-purity for formulations that can be injected
• It is a controlled format that requires management and storage
• COA MSDS as well as regulatory documentation available

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is Sugammadex Sodium used for?
   

   Used for rapid reversal of neuromuscular blockade induced by rocuronium or vecuronium during anesthesia, including routine and emergency situations.
   
   

2. How does Sugammadex work?
   

   It encapsulates rocuronium or vecuronium molecules in its cavity, forming inactive complexes that are excreted, thereby rapidly reducing free drug concentration and reversing muscle paralysis.
   
   

3. What are the advantages of neostigmine?
   

   Faster reversal, works at any depth of blockade, no ceiling effect, no muscarinic side effects, more predictable, and can be used in emergency situations.