Sodium Periodate | 7790-28-5

Description :

Overview of Sodium Periodate

Sodium Periodate is a strong oxidizing agent used in organic synthesis, analytical chemistry, and biochemistry for the selective oxidation of diols and related compounds. Known for its ability to cleave vicinal diols (Malaprade reaction), oxidize α-amino alcohols, and selectively oxidize specific functional groups, Sodium Periodate is widely used in carbohydrate chemistry, glycoprotein analysis, and organic synthesis.

This compound appears as a white crystalline powder or granules. Its periodate anion (IO₄⁻) with iodine in +7 oxidation state provides powerful and selective oxidizing capability.

Related products include Periodic Acid, Lead Tetraacetate, and other oxidizing agents used in organic chemistry and analytical applications. It may be used in reactions involving Diethyl Maleate and other substrates requiring selective oxidation.

Applications of Sodium Periodate

Organic Synthesis

• Used in oxidative cleavage of vicinal diols (Malaprade reaction)
• Applied in converting 1,2-diols to aldehydes or ketones
• Used in oxidizing α-amino alcohols
• Applied in carbohydrate chemistry modifications

Analytical Chemistry

• Used in carbohydrate structure determination
• Applied in glycoprotein analysis
• Used in histochemical staining (Periodic Acid-Schiff)
• Applied in identifying polysaccharides

Biochemistry & Research

• Used in protein glycosylation studies
• Applied to oxidizing carbohydrates in biomolecules
• Used in bioconjugation chemistry
• Applied in glycobiology research

Safety & Handling Guidelines

• STRONG OXIDIZER—keep away from combustible materials
• Avoid contact with reducing agents and organic materials
• Use gloves, goggles, and protective clothing
• Handle in well-ventilated areas
• Store in tightly closed containers away from incompatible materials
• Keep containers dry—moisture causes decomposition
• Follow COA and MSDS instructions strictly

Where to Buy Sodium Periodate?

Sodium Periodate Manufacturer

ChemicalBull provides the highest purity Sodium Periodate that meets the requirements of research and analytical quality.

Sodium Periodate Supplier & Distributor

• It is available in different sizes of packs to be used in laboratory or research purposes.
• Grades with high purity (99 percent, ACS Reagent grade)
• COA MSDS, along with specifications, is included.

MSDS

Complete safety instruction, including oxidizer alerts, as well as handling protocol.

Frequently Asked Questions (FAQs)

1. What is Sodium Periodate used for?
   

   Used in oxidative cleavage of vicinal diols, carbohydrate analysis, glycoprotein staining, biochemical oxidations, and selective organic synthesis transformations.
   
   

2. What is the molecular formula?
   

   Molecular formula: NaIO₄ with molecular weight 213.89 g/mol.
   
   

3. How does Sodium Periodate cleave diols?
   

   Forms a cyclic periodate ester intermediate from a vicinal diol, which decomposes, breaking the C-C bond to produce two carbonyl compounds.