Racecadotril | 81110-73-8

Description :

Overview of Racecadotril

Racecadotril is an anti-secretory antidiarrheal medication used in the treatment of acute diarrhea for both children and adults. It is renowned for its distinctive method of reducing the production of excessive intestinal fluids without impacting the gut's motility. Racecadotril is frequently utilized in gastroenterology as a treatment of symptoms associated with acute diarrhea with water while preserving the normal flow of intestinal blood.

This API appears as a white to slightly yellowish powder with limited water solubility. Its mechanism—inhibition of enkephalinase enzyme, leading to increased levels of endogenous enkephalins—reduces intestinal fluid and electrolyte secretion without causing constipation or affecting intestinal motility.

Related products include Loperamide, Bismuth Subsalicylate, oral rehydration salts, and other antidiarrheal agents. May be used alongside electrolyte solutions containing Fructose for rehydration support.

Applications of Racecadotril

Pharmaceutical API

• Used in antisecretory antidiarrheal medications
• Effective in treating acute watery diarrhea in adults and children
• Reduces stool output and frequency without affecting motility
• Applied to traveler's diarrhea and gastroenteritis
• Suitable for pediatric use (over 3 months of age)

Formulation Development

• Used in capsules, granules for oral suspension, and tablets
• Pediatric formulations available as sachets/granules
• Rapid onset of action (within 30 minutes to 1 hour)
• Can be combined with oral rehydration therapy
• Stable in solid dosage forms
• Multiple strength options for different age groups

Gastrointestinal Treatment

• Lowers the amount of intestinal secretions as well as the volume of stool.
• Maintains normal intestinal transit time (no constipation)
• does not conceal the underlying infection or hinder detection
• It is well-tolerated and has minimal adverse negative effects
• It is safe to use using antibiotics if necessary.
• Treatment for short-term use (typically between 3 and 7 days)

Safety & Handling Guidelines

• Beware of inhaling fine powder
• Wear gloves, goggles and protection clothing while handling
• Place in a dry and cool area away from water
• Be sure to follow COA and MSDS guidelines strict

Where to Buy Racecadotril?

Racecadotril Manufacturer

ChemicalBull supplies high-purity Racecadotril API that meets IP/EP/USP quality standards for pharmaceutical formulations.

Racecadotril Supplier & Distributor

• In bulk packaging to make formulation units
• Highly stable and pure for production and research
• COA MSDS along with other documents for regulatory purposes available

MSDS

Provides detailed safety guidelines as well as hazard identification and the storage requirements.

Frequently Asked Questions (FAQs)

1. What is the Racecadotril dosage?
   

   Adults: 100 mg three times daily; Children: dose based on body weight (1.5 mg/kg three times daily). Treatment usually continues until diarrhea stops, typically 3-7 days.
   
   

2. What is Racecadotril medicine used for?
   

   Racecadotril is used for symptomatic treatment of acute diarrhea in adults and children, reducing stool frequency and volume while maintaining normal gut function.
   
   

3. How does Racecadotril work?
   

   It inhibits the enkephalinase enzyme, increasing enkephalin levels in the intestine, thereby reducing water and electrolyte secretion into the intestinal lumen without affecting motility.