Quinine Hydrochloride | 130-89-2

Description :

Overview of Quinine Hydrochloride

Quinine Hydrochloride is an antimalarial alkaloid derived from cinchona bark used for treating malaria and nocturnal leg cramps. Known for its schizontocidal activity against Plasmodium species and muscle relaxant properties, Quinine Hydrochloride is widely used in tropical medicine, emergency malaria treatment, and as a therapeutic agent for severe muscle cramping.

This API appears as a white to off-white crystalline powder or fine needles with a bitter taste and good water solubility. Its mechanism—interference with parasite DNA replication and transcription, plus direct effects on muscle membrane—provides effective antimalarial action and relief from severe muscle cramps.

Related products include Chloroquine, Artemisinin derivatives, Hydroxychloroquine, and other antimalarial agents used in the management of tropical diseases and autoimmune conditions.

Applications of Quinine Hydrochloride

Pharmaceutical API

• Used in antimalarial medications for treating chloroquine-resistant Plasmodium falciparum malaria
• Effective in treating severe and complicated malaria
• Applied in the treatment of nocturnal leg cramps and muscle spasms
• Used in combination therapy with other antimalarials (doxycycline, clindamycin)
• Historical use in treating babesiosis

Formulation Development

• Used in injectable solutions for severe malaria
• Available in oral tablets and capsules
• Requires careful pH control in formulations
• Light-sensitive—requires protection during manufacturing
• Often formulated with acidulants to improve stability
• Bitter taste requires masking in oral formulations

Antimalarial & Therapeutic Treatment

• Rapidly reduces parasitemia in severe malaria
• The HTML0 is a serious complication of malaria
• Relieves painful nocturnal leg cramps
• Requires monitoring during treatment (cardiac effects)
• Alternative, when first-line antimalarials cannot be found
• Life-saving in severe malaria cases

Safety & Handling Guidelines

• Do not inhale fine powder
• Make sure you wear gloves, goggles, and appropriate clothing when handling
• Beware of sunlight
• Store in a dry, cool location away from light and humidity
• Use COA as well as MSDS guidelines strictly

Where to Buy Quinine Hydrochloride?

Quinine Hydrochloride Manufacturer

ChemicalBull supplies high-purity Quinine Hydrochloride API that meets IP/EP/USP quality standards for pharmaceutical formulations.

Quinine Hydrochloride Supplier & Distributor

• Available in bulk packing for formulation units
• Stable and high-purity grade for research and production
• COA, MSDS, and regulatory documents provided

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

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