Propargyl Alcohol | 107-19-7

Description :

Overview of Propargyl Alcohol

Propargyl Alcohol (2-Propyn-1-ol) is an organic substance that contains the terminal alkyne as well as hydroxyl functional groups. It is utilized as a flexible component for chemical synthesis, manufacturing of pharmaceuticals, and as an inhibitor of corrosion. It is renowned for its dual-purpose function, which allows many chemical transformations. Propargyl Alcohol is widely used to synthesize pharmaceuticals, agrochemicals, and special chemicals.

The compound is a transparent to pale yellow liquid that has a distinctive smell. The terminal alkyne, when combined with the alcohol of primary, provides an extraordinary synthetic flexibility for coupling reactions, click chemistry, as well as transformations of functional groups.

Similar products are Allyl Alcohol, Propargylamine, Diethyl Oxalate, as well as various propargylic and alkyne intermediates for organic syntheses.

Applications of Propargyl Alcohol

Pharmaceutical Synthesis

• It is used to synthesize pharmaceutical intermediates
• Used in the preparation of pharmaceutical molecules containing alkyne moieties
• Utilized in click chemistry (CuAAC) for the purpose of drug conjugation
• Used in the preparation of propargylethers
• Utilized in the production of bioactive substances
• Used in medicinal chemistry research
• Utilized in the development of APIs for pharmaceuticals.
• Utilized for fragment-based discovery of drugs

Organic Synthesis

• It is used for the Sonogashira reaction of coupling
• Apply to Nicholas reaction
• It is used in the preparation of β-unsaturated carbonyl compounds
• Used in the process of synthesizing heterocyclic compounds
• used in alkynylation reactions
• Used in the preparation of propargylic derivatives
• Utilized in the complete synthetic process of natural ingredients
• Applied in developing new synthetic methodologies

Industrial Applications

• It is used to prevent corrosion in treating metals
• Applied in electroplating baths
• It is used in the manufacturing of special polymers
• Used in the production of agricultural chemical intermediates
• It is used to prepare surfactants
• Applied in developing performance chemicals
• It is used in materials science and engineering applications
• Applied in coating formulations

Safety & Handling Guidelines

• highly toxic and extremely flammable. Handle carefully
• Beware of inhaling the vapors
• Make sure you wear goggles, gloves, and protective clothes
• Handle inside a ventilated fume Hood
• Keep in tightly sealed containers, away from fire and heat
• Stay clear of the oxidizing agents as well as the strong acidic substances.
• May polymerize--stabilizers may be added.
• Use the COA as well as the MSDS guidelines strictly

Where to Buy Propargyl Alcohol?

Propargyl Alcohol Manufacturer

ChemicalBull supplies high-purity Propargyl Alcohol, meeting pharmaceutical and research quality standards.

Propargyl Alcohol Supplier & Distributor

• Available in bulk quantities for pharmaceutical and research use
• High-purity grades (98%, 99%)
• Stabilized or unstabilized options available
• COA, MSDS, and specifications provided

MSDS

Includes detailed safety instructions, flammability warnings, toxicity information, and handling protocols.

Frequently Asked Questions (FAQs)

1. What is Propargyl Alcohol CAS No?
   

   CAS number: 107-19-7.
   
   

2. What is Propargyl Alcohol's structure?
   

   Contains terminal alkyne and primary alcohol; HC≡CCH₂OH; molecular formula C₃H₄O.
   
   

3. What is the molecular weight of Propargyl Alcohol?
   

   Molecular weight: 56.06 g/mol.