Pravastatin Sodium | 81131-70-6
Cas No :
81131-70-6
Form :
Solid
Molecular Weight :
446.52
Molecular Formula :
C23H35NAO7
Melting Point :
171,2 - 173 °C
Description :
Overview of Pravastatin Sodium
Pravastatin sodium is an HMG CoA reductase inhibitor (statin) utilised to treat hypercholesterolemia as well as to prevent the development of cardiovascular diseases. The drug is known for its hydrophilic characteristics and the proven benefits for cardiovascular health. Pravastatin Sodium is widely utilised in the treatment of lipids as well as the treatment of cardiovascular risk reduction.
This API appears as a white to off-white powder with good water solubility and specific storage requirements. Its mechanism—competitive inhibition of HMG-CoA reductase enzyme—reduces cholesterol synthesis in the liver, lowering LDL cholesterol, total cholesterol, and triglycerides while modestly increasing HDL cholesterol.
Related products include Atorvastatin, Simvastatin, Rosuvastatin, and other statin medications used in dyslipidemia management and cardiovascular disease prevention.
Applications of Pravastatin Sodium
Pharmaceutical API
- Utilised in medications to lower lipids to treat hypercholesterolemia.
- Highly effective for both secondary and primary prevention of heart attacks
- Reduces the risk of myocardial infarction, stroke and the death of a cardiovascular patient
- treats mixed dyslipidemia as well as familial hypercholesterolemia
- It is used by diabetic patients to provide cardiovascular protection
Formulation Development
- used in tablets that release immediately
- requires protection against moisture and light
- Dosing formulas that are once a day (evening administration preferred)
- Available in various strengths (10, 20, 40, 80 mg)
- Stable when properly prepared and sealed tablets
Cardiovascular Treatment
- Significantly lowers LDL cholesterol (20-40 per cent reduction)
- Lowers total cholesterol levels and the triglyceride S
- A slight rise in HDL cholesterol
- The hydrophilic nature reduces tissue penetration (lower risk of certain side effects)
- Safety and effectiveness Profile
Safety & Handling Guidelines
- Beware of inhaling fine powder
- Make sure you wear gloves, goggles, or appropriate clothing when handling
- Keep it in a dry, cool location, away from moisture and light
- Requires refrigerated storage for bulk API
- Be sure to follow COA and MSDS guidelines completely
Where to Buy Pravastatin Sodium?
Pravastatin Sodium Manufacturer
ChemicalBull supplies high-purity Pravastatin Sodium API that meets IP/EP/USP quality standards for pharmaceutical formulations.
Pravastatin Sodium Supplier & Distributor
- Available in bulk packing for formulation units
- Stable and high-purity grade for research and production
- Requires controlled storage conditions
- COA, MSDS, and regulatory documents provided
MSDS
Includes detailed safety instructions, hazard identification, and storage guidelines.
Frequently Asked Questions (FAQs)
-
What is Pravastatin Sodium used for?
It is used for lowering cholesterol levels and reducing the risk of heart attack, stroke, and other cardiovascular events. -
What is the difference between Pravastatin and other statins?
Pravastatin is hydrophilic (water-soluble), unlike most statins, which are lipophilic, potentially resulting in different side effect profiles and drug interactions. -
When should Pravastatin be taken?
It is typically taken once daily in the evening, with or without food, as cholesterol synthesis is highest at night.