N,O-Bis-Trimethylsilyl Trifluoroacetamide | 25561-30-2

Cas No :

25561-30-2

Form :

Liquid

Molecular Weight :

257.41 G/Mol

Molecular Formula :

C8H18F3NOSI2

Boiling Point :

125 °C

Melting Point :

-65 °C

Flash Point :

20 °C

Solubility :

Soluble In Nonpolar Organic Solvents; Insoluble In Water

Description :

Overview of N,O-Bis-Trimethylsilyl Trifluoroacetamide

N,O-Bis-Trimethylsilyl Trifluoroacetamide (BSTFA) is a high-reactivity organosilicon compound widely used as an industrial derivatization reagent and functionalization agent. It is mostly used for the introduction of trimethylsilyl (TMS) groups into organic molecules that contain carboxyl, hydroxyl, or thiol functional groups.

As an industrial chemical, BSTFA is valued for its efficiency in improving volatility, thermal stability, and analytical performance of organic compounds in controlled manufacturing and laboratory environments.


Applications of N,O-Bis-Trimethylsilyl Trifluoroacetamide

Industrial Analytical Processing

BSTFA is extensively used in industrial analytical laboratories for derivatization prior to gas chromatography (GC) and GC-MS analysis. It converts polar compounds into volatile trimethylsilyl derivatives for precise quality control and impurity profiling.

It may be used alongside Dimethyl Sulfoxide AR, Acetone AR, and Methanol AR in structured industrial testing systems.

Pharmaceutical & Fine Chemical Manufacturing

N,O-Bis-Trimethylsilyl Trifluoroacetamide is applied in pharmaceutical manufacturing to support structural analysis, intermediate verification, and process validation under regulated industrial standards.

Organic & Specialty Chemical Synthesis

The compound functions as a silylating agent in industrial organic synthesis, enabling functional group protection and modification during multi-step production processes.

Research & Development Applications

BSTFA is widely used in R&D facilities for advanced molecular modification and analytical method development in the chemical and pharmaceutical industries.


Safety & Handling Guidelines

  • Storage inside tightly-sealed containers in an air-conditioned, dry environment.
  • Avoid humidity, since BSTFA reacts with water.
  • Beware of inhaling the vapors
  • Make sure you avoid contact with the eye and skin.
  • Use protective gloves, goggles, and appropriate industrial clothing
  • Handle under proper ventilation and controlled industrial conditions

Always review the MSDS before industrial handling.


Where to Buy N,O-Bis-Trimethylsilyl Trifluoroacetamide?

N,O-Bis-Trimethylsilyl Trifluoroacetamide Manufacturer

BSTFA is manufactured under strict industrial quality standards to ensure high purity and consistent reactivity for industrial analytical and synthesis applications.

N,O-Bis-Trimethylsilyl Trifluoroacetamide Supplier & Distributor

Buy N,O-Bis-Trimethylsilyl Trifluoroacetamide from Chemicalbull Pvt. Ltd., a trusted industrial chemicals supplier and distributor in India, providing dependable sourcing and compliant logistics support.

For bulk supply and pricing information, contact Chemicalbull Pvt. Ltd. for a competitive industrial quotation.


MSDS for N,O-Bis-Trimethylsilyl Trifluoroacetamide

The MSDS for N,O-Bis-Trimethylsilyl Trifluoroacetamide provides detailed information on hazard identification, safe handling procedures, storage requirements, exposure controls, and emergency response measures.


Frequently Asked Questions (FAQs)

  1. What is N,O-Bis-Trimethylsilyl Trifluoroacetamide used for?

    It is used as an industrial silylating and derivatization reagent in analytical testing, pharmaceutical manufacturing, and specialty chemical synthesis.

  2. What is the chemical formula of N,O-Bis-Trimethylsilyl Trifluoroacetamide?

    The chemical formula of BSTFA is C₈H₁₈F₃NOSi₂.

  3. What industries use N,O-Bis-Trimethylsilyl Trifluoroacetamide?

    It is widely used in pharmaceutical, chemical manufacturing, analytical testing, and research industries.