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Methyl Acetoacetate | 105-45-3

Cas No :

105-45-3

Synonyms :

Form :

Liquid

Molecular Weight :

116.12 G/Mol

Molecular Formula :

C5H8O3

Melting Point :

80 °C

Boiling Point :

169 - 170 °C

Solubility :

Chloroform, Methanol

Flash Point :

70 °C

Description :

Overview of Methyl Acetoacetate

Methyl Acetoacetate is a clear, colourless liquid with a pleasant, fruity odour. It is an ester of acetoacetic acid and methanol, widely used as a chemical intermediate in pharmaceuticals, agrochemicals, and dye industries. Its active methylene group makes it highly versatile in organic synthesis, enabling various condensation and substitution reactions.Methyl Acetoacetate is soluble in most organic solvents such as alcohols, esters, and ethers, but is only slightly soluble in water. Its stability, reactivity, and solvent compatibility make it valuable in industrial and laboratory applications.

Applications of Methyl Acetoacetate

Pharmaceuticals

It is used as an intermediate in the production of active pharmaceutical components (APIs), as well as vitamins and various other fine chemical compounds. It's a basic building block that produces heterocyclic compounds and speciality drugs.

Agrochemicals

It is used as a precursor in manufacturing pesticides, herbicides, and fungicides, thanks to its ester group that reacts.

Dyes & Pigments

Acts as an intermediate in the production of dyes, especially when it comes to the manufacturing of the azo dye as well as speciality colours.

Flavors & Fragrances

Provides fruity and sweet notes, and can be utilized as a flavouring agent or as a fragrance intermediary in the perfumery industry.

Laboratory & R&D

Used as a solvent and reagent for organic synthesis, specifically for reactions that require C-C bond formation, acylation and condensation of esters.

Safety & Handling Guidelines

  • Wear protective gloves, goggles, and clothing when handling concentrated Methyl Acetoacetate.

  • Avoid inhalation of vapours; use only in well-ventilated areas.

  • Store in tightly sealed containers, in a cool, dry, well-ventilated place, away from heat, flames, and oxidizing agents.

  • Prevent prolonged skin contact; wash thoroughly with soap and water if exposed.

  • Refer to the MSDS for toxicological details, first aid, and fire-fighting instructions.

Where to Buy Methyl Acetoacetate?

Methyl Acetoacetate Manufacturer in India:

ChemicalBull manufactures high-purity Methyl Acetoacetate, ideal for pharmaceutical, agrochemical, and industrial applications.

Methyl Acetoacetate Supplier in Vapi:

ChemicalBull supplies both bulk and small packaging with assured safe and timely delivery.

Methyl Acetoacetate Supplier in Vapi:

Available from ChemicalBull in multiple packaging options, meeting industrial requirements across Vapi and nearby regions.

Methyl Acetoacetate MSDS

For detailed information on hazards, environmental impact, toxicology, and handling precautions, request the Material Safety Data Sheet (MSDS) from ChemicalBull.

Frequently Asked Questions

  1. Is Methyl Acetoacetate water-soluble?

    It is only slightly soluble in water but highly soluble in alcohols, esters, and most organic solvents.

  2. What are the main uses of Methyl Acetoacetate?

    It is primarily used as a chemical intermediate in pharmaceuticals, agrochemicals, dyes, and organic synthesis.

  3. Where can I buy Methyl Acetoacetate?

    You can purchase it from ChemicalBull, a trusted manufacturer and supplier of high-quality esters and intermediates.

  4. Is Methyl Acetoacetate safe to use?

    Yes, when handled with appropriate safety measures. Avoid direct skin contact and inhalation of concentrated vapours.

  5. Can Methyl Acetoacetate be used in fragrance applications?

    Yes, it is sometimes used as a fragrance intermediate and can provide fruity notes in formulations.

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