Levosulpiride | 23672-07-3

Cas No :

23672-07-3

Form :

Solid

Molecular Weight :

341,43 G/Mol

Molecular Formula :

C15H23N3O4S

Melting Point :

183 - 186 °C

Solubility :

Dmso, Dmf, Methanol

Description :

Overview of Levosulpiride

 

Levosulpiride can be described as a substituted benzamide and selective antagonist of the dopamine D2 receptor that is used to treat dyspepsia, gastroesophageal reflux disorder (GERD), as well as depression and schizophrenia. The drug is known for its prokinetic as well as neuroleptic qualities. Levosulpiride is widely used in psychiatry and gastroenterology.

This API appears as a white to off-white crystalline powder with good stability under standard storage conditions. Its mechanism—selective antagonism of dopamine D2 receptors in both peripheral and central nervous systems—provides gastroprokinetic effects and antipsychotic/antidepressant actions.

Related products include Lafutidine, Lansoprazole, Metoclopramide, Domperidone, and other prokinetic and antipsychotic agents used in gastrointestinal and psychiatric therapy.

 

 

Applications of Levosulpiride

 

Pharmaceutical API

 

  • Used in prokinetic and antipsychotic medications
  • Effective in treating functional dyspepsia and GERD
  • Used for depression with somatic symptoms
  • Applied in the treatment of vertigo and migraine
  • Shows efficacy in certain psychotic disorders

 

Formulation Development

 

  • Used in tablets, sustained-release tablets, and capsules
  • Available in oral solution formulations
  • Suitable for combination formulations with gastroprotective agents like Lafutidine or Lansoprazole
  • Offers good bioavailability and stability

 

 

Gastrointestinal & Psychiatric Treatment

 

  • Improves gastric motility and speeds up gastric emptying
  • Reduces the symptoms of nausea, bloating, and epigastric discomfort.
  • Helps improve symptoms of depression, particularly with somatic complaints
  • Lower extrapyramidal side effect profile at lower doses

 

 

Safety & Handling Guidelines

 

  • Do not inhale fine powder
  • Use gloves, goggles, and protective clothing during handling
  • Place in a dry, cold location away from light water
  • Be sure to follow COA and MSDS guidelines completely

 

 

Where to Buy Levosulpiride?

 

Levosulpiride Manufacturer

 

ChemicalBull supplies high-purity Levosulpiride API that meets IP/EP/USP quality standards for pharmaceutical formulations.

 

Levosulpiride Supplier & Distributor

 

  • Available in bulk packing for formulation units
  • Stable and high-purity grade for research and production
  • COA, MSDS, and regulatory documents provided

 

 

MSDS

 

With detailed safety tips, as well as hazard identification and instructions for storage.

 

 

Frequently Asked Questions (FAQs)

 

  1. What exactly is Levosulpiride employed to treat?

    It's used in the treatment of dyspepsia, GERD, and depression that have emotional symptoms and other mental health conditions. disorders.

  2. Do you think Levosulpiride can be used in conjunction with acid-suppressants?

    It is used in conjunction with PPIs like Lansoprazole or H2 blockers like Lafutidine for complete GERD control.

  3. Does Levosulpiride have stability in Tablet formulation?

    It is indeed a great option, offering great stability and durability with strong dos older forms.