Lawesson's Reagent | 19172-47-5
Cas No :
19172-47-5
Form :
Powder
Molecular Weight :
349.60 G/Mol
Molecular Formula :
C14H14O2P2S4
Melting Point :
110 °C
Boiling Point :
260 °C
Solubility :
Soluble In Dichloromethane And Toluene; Insoluble In Water
Flash Point :
150 °C
Description :
Overview of Lawesson's Reagent
Lawesson's Reagent (C₁₄H₁₄O₂P₂S₄) is a powerful organophosphorus compound widely used as a thionation agent in organic synthesis. It is a yellow crystalline solid known for its ability to convert carbonyl groups into thiocarbonyls, making it an essential reagent in pharmaceutical, agrochemical, and material chemistry research.
This reagent is extremely valuable in synthesizing thioamides, thioketones, thiolactones, and sulphur-containing heterocycles. Due to its high reactivity, Lawesson's Reagent is commonly used in R&D laboratories, chemical research institutions, and specialty chemical production.
Other related products available on our website include Phosphorus Pentasulfide, Thionyl Chloride, and Thiourea, which are widely used in thionation and sulphur-based synthesis processes.
Applications of Lawesson's Reagent
Pharmaceutical Industry
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Used to synthesize thioamides, key intermediates in drug development
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Helps create sulfur-based analogs in medicinal chemistry
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Used in the preparation of biologically active heterocycles
Organic Synthesis
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Converts carbonyl compounds into thiocarbonyl derivatives
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Essential for producing thiolactams, thioureas, and thiophenes
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Used in structural modification of organic molecules
Agrochemical Research
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Helps produce sulfur-containing pesticides and herbicides
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Serves as a reagent in synthesizing biologically active compounds
Polymer & Material Science
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Used in preparing sulfur-rich polymers
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Helps synthesize advanced materials with improved stability and performance
R&D Chemistry
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Common in academic and industrial research labs
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Ideal for multi-step organic transformations requiring sulfur insertion
Safety & Handling Guidelines
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Toxic if inhaled, ingested, or absorbed through skin
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Causes severe irritation to eyes, skin, and respiratory tract
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Use gloves, mask, goggles, and proper ventilation
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Avoid contact with moisture
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Store in a cool, dry place away from oxidizing agents
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Always follow MSDS instructions for handling, storage, and disposal
Where to Buy Lawesson's Reagent?
Lawesson's Reagent Manufacturer
ChemicalBull provides high-quality Lawesson's Reagent suitable for pharmaceutical synthesis, lab research, and specialty chemical applications.
Lawesson's Reagent Supplier & Distributor
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Available in research-grade and bulk packaging
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COA, TDS & MSDS provided with every order
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Fast and reliable domestic & international supply
Lawesson’s Reagent MSDS
The MSDS contains detailed information on hazards, protective measures, and safe storage requirements. Review MSDS carefully before use.
Frequently Asked Questions (FAQs)
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What is Lawesson's Reagent used for?
It is used as a thionation agent to convert carbonyl compounds into thiocarbonyl derivatives in pharmaceutical and chemical synthesis. -
Is Lawesson's Reagent hazardous?
Yes. It is toxic and can cause severe irritation. Proper PPE and lab safety measures are essential. -
Is Lawesson's Reagent soluble in solvents?
It is soluble in organic solvents such as toluene, dichloromethane, and THF.