Ezetimibe | 163222-33-1
Cas No :
163222-33-1
Form :
Solid
Molecular Weight :
409.43 G/Mol
Molecular Formula :
C24H21F2NO3
Boiling Point :
390 °C
Melting Point :
82 °C
Flash Point :
230 °C
Solubility :
Sparingly Soluble In Water; Soluble In Methanol, Ethanol, Acetone
Description :
Overview of Ezetimibe
Ezetimibe is a widely used cholesterol-lowering pharmaceutical compound prescribed for reducing LDL (bad cholesterol) levels in patients with hyperlipidemia. It works by selectively inhibiting cholesterol absorption in the small intestine, leading to improved lipid profiles. In formulation and manufacturing environments, Ezetimibe may be evaluated alongside other excipients and chemical aids similar to how Methyl Linoleate and Sodium Tolyltriazole are used in enhancing stability and performance during pharmaceutical processing.
The chemical formula of Ezetimibe is C₂₄H₂₁F₂NO₃, and it typically appears as a white to off-white crystalline powder. It is commonly used in oral dosage forms, including tablets and fixed-dose combinations with statins for enhanced cardiovascular benefits.
Applications of Ezetimibe
Pharmaceutical Formulations
- Active ingredient in cholesterol-lowering medications
- Used in single-ingredient and combination (statin + Ezetimibe) tablets
- Effective in reducing LDL cholesterol and total lipid levels
Medical & Clinical Research
- Studied for its impact on cardiovascular risk reduction
- Evaluated in metabolic syndrome and lipid disorder research
- Used in pharmacokinetic and drug absorption studies
Industrial & Laboratory Use
- Applied in QC testing and formulation development
- Used in reference standards for analytical studies
- Supports pharmaceutical R&D and regulatory submissions
Safety & Handling Guidelines
- Use gloves, goggles, and laboratory-grade protective clothing
- Avoid inhalation of fine powder
- Handle in a properly ventilated or controlled workspace
- Store in airtight containers away from heat and humidity
- Refer to MSDS before handling large or bulk quantities
Where to Buy Ezetimibe?
Ezetimibe Manufacturer
ChemicalBull supplies pharmaceutical-grade Ezetimibe suitable for formulation development, commercial production, and laboratory research.
Ezetimibe Supplier & Distributor
- Available in bulk and export-quality packaging
- COA, TDS, and MSDS provided with every batch
- Reliable supply for pharma manufacturers and research organizations
Ezetimibe MSDS
The MSDS provides complete safety details, including toxicity information, hazard identification, safe handling measures, storage recommendations, accidental release protocols, and emergency response guidelines.
Frequently Asked Questions (FAQs)
-
What is the formula of Ezetimibe?
The chemical formula is C₂₄H₂₁F₂NO₃. -
What is Ezetimibe used for?
It is used to lower LDL cholesterol and improve lipid levels. -
Is Ezetimibe used alone or with other drugs?
It is used alone or in combination with statins for improved results. -
Is Ezetimibe safe to handle?
Yes, when proper PPE and MSDS guidelines are followed. -
Is Ezetimibe water-soluble?
It has very low water solubility but works effectively as an oral medication.