Epirubicin Hydrochloride | 56390-09-1

Cas No :

56390-09-1

Synonyms :

Form :

Solid

Molecular Weight :

579.98 

Molecular Formula :

C27H29NO11·HCL 

Description :

Overview of Epirubicin Hydrochloride

 

Epirubicin Hydrochloride can be described as an anthracycline-based antineoplastic drug which is utilized to treat various cancers like breast cancer, stomach cancer, lung cancer and lymphomas. The drug is renowned for its potent cell-killing activity as well as its improved quality of life compared to the doxorubicin drug, Epirubicin Hydrochloride has been extensively utilized in the field of oncology to treat chemotherapy.

This API appears as a red to orange-red lyophilized powder with light sensitivity and requires careful handling. Its mechanism—intercalation into DNA, inhibition of topoisomerase II, and generation of free radicals—leads to DNA damage, disruption of cellular replication, and cancer cell death.

Related products include Doxorubicin, Daunorubicin, Idarubicin, and other anthracycline chemotherapy agents used in various cancer treatment protocols.

 

 

Applications of Epirubicin Hydrochloride

 

Pharmaceutical API

 

  • Used in antineoplastic chemotherapy medications
  • Effective in treating breast cancer (adjuvant and metastatic settings)
  • Used in gastric, ovarian, lung, and bladder cancers
  • Applied in lymphoma and leukemia treatment
  • Component of combination chemotherapy regimens (e.g., FEC, EC protocols)

 

Formulation Development

 

  • Used in lyophilized powder for injection
  • Requires reconstitution before administration
  • Available in various strengths for IV infusion
  • Highly potent—requires specialized handling and preparation
  • Protected from light during storage and administration

 

Oncological Treatment

 

  • Provides dose-dependent cytotoxic effects
  • Lower cardiotoxicity compared to doxorubicin at equivalent doses
  • Used in both curative and palliative settings
  • Administered as part of multi-agent chemotherapy protocols
  • Requires cardiac monitoring during treatment

 

 

Safety & Handling Guidelines

 

  • CYTOTOXIC DRUG—requires specialized containment and handling
  • Use appropriate PPE including double gloves, gown, and eye protection
  • Handle in biological safety cabinet or isolator
  • Avoid inhalation, skin contact, and ingestion
  • Protect from light exposure

 

 

Where to Buy Epirubicin Hydrochloride?

 

Epirubicin Hydrochloride Manufacturer

 

ChemicalBull supplies high-purity Epirubicin Hydrochloride API, meeting IP/EP/USP quality standards for pharmaceutical formulations.

 

Epirubicin Hydrochloride Supplier & Distributor

 

  • Available in bulk packing for formulation units with cytotoxic containment
  • Stable and high-purity grade for oncology production
  • COA, MSDS, and regulatory documents provided
  • Specialized packaging and shipping for cytotoxic materials

 

 

MSDS

 

Includes detailed safety instructions, hazard identification, cytotoxic handling protocols, and storage guidelines.

 

 

Frequently Asked Questions (FAQs)

 

  1. What is Epirubicin Hydrochloride molecular weight?

    The molecular weight of Epirubicin Hydrochloride is approximately 579.98 g/mol.

  2. What are Epirubicin uses?

    Epirubicin is used for treating breast cancer, gastric cancer, ovarian cancer, lung cancer, bladder cancer, and various lymphomas as part of chemotherapy regimens.

  3. What is the use of Epirubicin Hydrochloride?

    It is used as a chemotherapy agent to kill cancer cells by damaging their DNA and preventing their replication, typically administered intravenously.