Dimethylacetamide | 127-19-5

Description :

An Overview of Dimethylacetamide

Dimethylacetamide (DMAc or DMAC) is one of the polar aprotic solvents that is widely utilised in pharmaceutical manufacturing as well as polymer processing and chemical synthesis. It is renowned for its outstanding solution for pharmaceuticals and polymers, as well as its high boiling point and miscibility with water and the majority of organic solvents. Dimethylacetamide is extensively used for the production of membranes, fibres, and also as a catalyst for drug syntheses.

The substance appears as a transparent liquid, with an ammonia-like smell. Its amide structure offers excellent Polar aprotic properties to dissolve tough substrates.

Related products include Dimethylformamide (DMF), Dimethyl Sulfoxide (DMSO), N-Methyl-2-pyrrolidone (NMP), and other polar aprotic solvents used in pharmaceutical and polymer applications.

Applications of dimethylacetamide

Pharmaceutical Manufacturing

• It is used as a reaction solvent for API synthesis
• It is used in the process of pharmaceutical crystallisation
• Utilised in the process of preparing pharmaceutical solutions for processing drugs
• Utilised in the manufacture of specific injectable formulations
• Utilised in the synthesis of the action of antibiotics and other medicines
• Utilised in manufacturing intermediates for pharmaceuticals

Polymer Processing

• It is used in the spinning of solutions for polyamide and acrylic fibres
• It is used in the manufacture of membranes made from a polymer
• Utilised in the processing of polyurethanes
• Utilised in the manufacture of speciality fibres (Nomex, Kevlar)
• Utilised in membrane filtration applications
• Apply to the electrodes for lithium batteries

Chemical Synthesis

• It is used as a reaction medium for reactions that are sensitive
• Used in the reaction of metal-catalysed coupling
• Utilised as an SNAr response
• Utilized to the condensation reaction
• Utilised in the development of pharmaceutical intermediates
• Used in the synthesis of agrochemicals

Safety and Guidelines for Handling

• Toxins that cause reproductive harm, avoid exposure to them, particularly during pregnancy.
• Beware of inhaling vapours
• Wear gloves, goggles, or protective clothing while handling
• Use in areas that are well ventilated or with a fume Hood
• Skin absorption possible--use appropriate gloves
• Storage in tightly sealed containers, away from the heat
• Use all exposure limits for occupational use. limit
• Be sure to follow COA and MSDS directions completely

Where to Buy Dimethylacetamide?

Dimethylacetamide Manufacturer

ChemicalBull supplies high-purity Dimethylacetamide (DMAc), meeting pharmaceutical and industrial quality standards.

Dimethylacetamide Supplier & Distributor

• Available in bulk quantities for pharmaceutical and industrial use
• High-purity grades (99%, 99.9%)
• Pharmaceutical and technical grades
• COA, MSDS, and specifications provided

MSDS

Includes detailed safety instructions, reproductive hazard information, and exposure guidelines.

Frequently Asked Questions (FAQs)

1. What is Dimethylacetamide used for?
   

   Used as a polar aprotic solvent in pharmaceutical synthesis, polymer fibre spinning, membrane manufacturing, and various chemical processes.
   
   

2. What is the molecular formula?
   

   Chemical formula: C₄H₉NO or CH₃CON(CH₃)₂ with molecular weight 87.12 g/mol.
   
   

3. How does DMAc compare to DMF?
   

   Similar polarity and solvent properties; DMAc has a slightly higher boiling point, slightly lower toxicity than DMF; both are reproductive toxins requiring caution.