Dicyclohexylurea | 2387-23-7

Cas No :

2387-23-7

Form :

Solid

Molecular Weight :

224.35

Molecular Formula :

C13H24N2O

Solubility :

Dmso (Slightly, Heated), Methanol (Slightly)

Description :

Overview of Dicyclohexylurea

 

Dicyclohexylurea (DCU) is an organic compound formed as a byproduct in peptide synthesis and other coupling reactions. Known for its formation in reactions using dicyclohexylcarbodiimide (DCC), easy removal by filtration, and use as an indicator of coupling reaction completion, Dicyclohexylurea is encountered in pharmaceutical synthesis, peptide chemistry, and organic synthesis.

This compound appears as a white crystalline solid with poor solubility in most solvents. Its dicyclohexylurea structure makes it easily separable from reaction products.

Related products include Dicyclohexylcarbodiimide (DCC), N, N'-Diisopropylcarbodiimide (DIC), and other coupling reagents used in peptide synthesis.

 

 

Applications of Dicyclohexylurea

 

Peptide Synthesis

 

  • It was created as a byproduct of DCC-mediated coupling
  • Used in the peptide bond-forming reactions
  • It is used as an indicator of the completion of coupling

 

Pharmaceutical Synthesis

 

  • Byproduct in pharmaceutical intermediate production
  • Used in esters and the formation of amide
  • It is used in the synthesis of drugs by using DCC

 

Organic Synthesis

 

  • Organic reaction of coupling
  • It is used in the specialty chemical synthesis
  • In the chemical intermediate manufacturing process

 

 

Safety & Handling Guidelines

 

  • Avoid inhalation of dust
  • Use gloves and protective clothing
  • Handle in well-ventilated areas
  • Store in tightly closed containers in a cool, dry place
  • Keep away from strong oxidizing agents
  • Dispose of according to organic waste protocols
  • Follow COA and MSDS instructions strictly

 

 

Where to Buy Dicyclohexylurea?

 

Dicyclohexylurea Manufacturer

 

ChemicalBull supplies Dicyclohexylurea for research applications and as a reference standard.

 

Dicyclohexylurea Supplier & Distributor

 

  • Available in various pack sizes for research use
  • High-purity grades (98%, 99%)
  • Reference standard quality
  • COA, MSDS, and specifications provided

 

 

MSDS

 

Includes detailed safety instructions and handling protocols.

 

 

Frequently Asked Questions (FAQs)

 

  1. What is Dicyclohexylurea?

    A byproduct is formed when using dicyclohexylcarbodiimide (DCC) coupling reagent in peptide synthesis and amide formation.

  2. What is the molecular formula?

    Molecular formula: C₁₃H₂₄N₂O with molecular weight 224.34 g/mol.

  3. How is it formed?

    Formed when DCC activates carboxylic acid; nucleophilic attack produces the desired product and DCU byproduct.