Dextromethorphan | 125-71-3

Description :

Overview of Dextromethorphan

Dextromethorphan is a centrally-acting cough suppressant, which is prescribed to treat dry, non-productive cough that is associated with influenza, colds and respiratory illnesses. It is known for its antitussive effects as well as NMDA receptor antagonistic properties, Dextromethorphan is widely used for prescription and over-the counter cold and cough formulations.

This API appears as a white to slightly yellow crystalline powder with good stability under standard storage conditions. Its mechanism—suppression of the cough reflex through action on the medullary cough centre—provides effective relief from persistent dry cough without the addictive properties of opioid antitussives.

Related products include Codeine, Diphenhydramine, Guaifenesin, and other antitussive and expectorant agents used in respiratory therapy and cough-cold medications.

Applications of Dextromethorphan

Pharmaceutical API

• Used in antitussive medications and cough suppressant formulations
• Effective in treating dry, non-productive cough
• Non-opioid alternative to codeine-based cough suppressants
• Used in various cough-cold combination products

Formulation Development

• Used in syrups, tablets, sustained-release capsules, and lozenges
• Suitable for combination formulations with antihistamines, decongestants, and expectorants
• Available in immediate-release and extended-release formulations
• Offers excellent stability in liquid and solid dosage forms

Respiratory Treatment

• Provides rapid relief from a persistent dry cough
• Helps improve sleep quality disrupted by coughing
• Non-sedating at therapeutic doses
• Suitable for pediatric and adult populations

Safety & Handling Guidelines

• Avoid inhalation of fine powder
• Use gloves, goggles, and protective clothing during handling
• Store in a cool, dry place away from light and moisture
• Follow COA and MSDS instructions strictly

Where to Buy Dextromethorphan?

Dextromethorphan Manufacturer

ChemicalBull supplies high-purity Dextromethorphan API that meets IP/EP/USP quality standards for pharmaceutical formulations.

Dextromethorphan Supplier & Distributor

• Available in bulk packing for formulation units
• Stable and high-purity grade for research and production
• COA, MSDS, and regulatory documents provided

MSDS

Includes detailed safety instructions, hazard identification, and storage guidelines.

Frequently Asked Questions (FAQs)

1. What is Dextromethorphan used for?
   

   It is used to suppress a dry, non-productive cough associated with respiratory infections and irritations.
   
   

2. What is the main ingredient in Dextromethorphan?
   

   Dextromethorphan itself is the active pharmaceutical ingredient, available as dextromethorphan hydrobromide or dextromethorphan polistirex.
   
   

3. What are the uses of Dextromethorphan?
   

   Dextromethorphan is used to suppress coughs in conditions such as the common cold, flu, bronchitis, and other respiratory tract infections that cause a dry cough.
   
   

4. Is Dextromethorphan habit-forming?
   

   At therapeutic doses, Dextromethorphan is not considered addictive like opioid cough suppressants, though misuse at high doses can occur.
   
   

5. How does Dextromethorphan work?
   

   It acts on the cough centre in the medulla oblongata of the brain, raising the cough threshold and suppressing the cough reflex.