Climbazole | 38083-17-9

Cas No :

38083-17-9

Synonyms :

Form :

Powder

Molecular Weight :

292.76 G/Mol

Molecular Formula :

C15H17CLN2O2

Melting Point :

96–100 °C

Boiling Point :

447.5 °C

Solubility :

Insoluble In Water; Soluble In Ethanol, Propylene Glycol;

Description :

Overview of Climbazole

Climbazole is an effective antifungal active ingredient widely used in anti-dandruff and scalp care formulations. It helps control dandruff, scalp flaking, itching, and fungal growth, mainly caused by Malassezia species. Due to its targeted action and good skin compatibility, Climbazole is commonly used in shampoos, scalp serums, lotions, and creams.

The CAS number of Climbazole is 38083-17-9. It is generally available as a white to off-white crystalline powder and is suitable for rinse-off and leave-on cosmetic formulations when used within recommended limits.


Application of Climbazole

Anti-Dandruff Shampoos and Hair Care Products

Climbazole shampoo is widely used to reduce visible dandruff and maintain scalp hygiene. It works by controlling fungal growth on the scalp, which helps reduce itching and flakes. Many formulations combine Climbazole with ingredients like Zinc Pyrithione or Piroctone Olamine to improve overall scalp performance.

Climbazole is suitable for regular anti-dandruff maintenance when formulated correctly.

Scalp Serums and Leave-On Treatments

Scalp serum with Climbazole is used in targeted dandruff control products. These serums help calm irritated scalp conditions and support long-term dandruff management. Climbazole works well in combination with conditioning agents like Panthenol to maintain scalp comfort.

Creams and Lotions

Climbazole cream and Climbazole lotion are used in cosmetic formulations meant for fungal-related skin concerns. These products are designed to maintain skin balance and prevent fungal overgrowth. In such formulations, Climbazole is often paired with mild emollients like Cetyl Alcohol for better skin feel.

Comparison with Other Antifungal Actives

When comparing Climbazole vs Ketoconazole, Climbazole is generally preferred in cosmetic and personal care products due to its better cosmetic acceptability and suitability for daily-use formulations. Ketoconazole is mainly used in medicated products, while Climbazole fits well in cosmetic-grade applications.

Pharmaceutical and Industrial Use

Climbazole is mainly used in cosmetic and personal care products rather than pharmaceutical drugs. It offers good antifungal activity at low concentrations, making it cost-effective and stable in formulations.

Its solubility in water is very low, so it is usually dissolved in solvents or oils during formulation.


Safety and Handling Guidelines

  • Store in a cool and dry place

  • Keep containers tightly closed

  • Avoid direct inhalation of dust

  • Use gloves while handling in bulk

  • Follow recommended usage limits in formulations

When used as per guidelines, Climbazole is considered safe and stable.


Where to Buy Climbazole

Climbazole Manufacturer

Climbazole is manufactured under controlled conditions to ensure purity, consistency, and compliance with cosmetic regulations.

Climbazole Supplier & Distributor

Chemicalbull supplies Climbazole for cosmetic and personal care products. As a Climbazole manufacturer and distributor, trader and exporter, our focus is on authentic materials, correct documentation, and dependable supplies for formulators and brands.

Climbazole is commonly sourced along with related ingredients such as Ketoconazole, Salicylic Acid, Zinc Pyrithione, Piroctone Olamine, and Panthenol for complete scalp care solutions.


MSDS for Climbazole

The Material Safety Data Sheet (MSDS) for Climbazole is available upon request and includes information related to handling, storage, safety measures, and regulatory details.


Frequently Asked Questions (FAQs)

  1. What is Climbazole used for?

    Climbazole is used to control dandruff, fungal scalp conditions, and itching in hair and scalp care products.

  2. Can I use Climbazole shampoo daily?

    Yes, Climbazole shampoo can be used regularly if the formulation is designed for daily use and follows recommended limits.

  3. Is Climbazole safe for the skin?

    Yes, Climbazole is considered safe for skin when used within approved cosmetic concentrations.

  4. What are the side effects of Climbazole?

    Side effects are rare, but very sensitive skin may experience mild irritation in some cases.

  5. What is the mechanism of action of Climbazole?

    Climbazole works by inhibiting fungal cell membrane function, which helps control dandruff-causing fungi.