Cetirizine Dihydrochloride | 83881-52-1

Cas No :

83881-52-1

Form :

Powder 

Molecular Weight :

461,81 G/Mol

Molecular Formula :

C21H25CLN2O3·2HCL

Boiling Point :

300 °C

Melting Point :

225 °C

Flash Point :

170 °C

Solubility :

Soluble In Water; Soluble In Methanol; Slightly Soluble In Ethanol

Description :

Overview of Cetirizine Dihydrochloride

Cetirizine Dihydrochloride is a second-generation antihistamine widely used in the pharmaceutical industry for the treatment of allergic conditions such as hay fever, urticaria, and other histamine-mediated disorders. It works by selectively inhibiting peripheral H1 receptors, providing effective relief from sneezing, itching, and watery eyes with minimal sedation.

Cetirizine Dihydrochloride is the standard globally recognized name for this API and is commonly referenced in pharmacopeia guidelines, pharmaceutical regulatory documents, clinical formulations, and safety data sheets.

 

Applications of Cetirizine Dihydrochloride

Pharmaceutical Formulations

Used in tablets, capsules, syrups, and oral suspensions for allergy relief. Often combined with decongestants like Pseudoephedrine for enhanced efficacy in combination therapies.


Allergy & Respiratory Therapy

Cetirizine Dihydrochloride effectively treats seasonal and perennial allergic rhinitis, chronic urticaria, and other hypersensitivity reactions.


Pediatric & Geriatric Applications

Formulated in liquid syrups and dispersible tablets for safe use in children and the elderly, ensuring accurate dosing and reduced sedation.


Research & Development

Applied in pharmaceutical R&D for developing advanced antihistamine formulations, combination therapies, and novel delivery systems.


Safety & Handling Guidelines

  • Store in a cool, dry, well-ventilated place

  • Keep containers tightly sealed to prevent contamination

  • Avoid inhalation of powder; use gloves, goggles, and PPE

  • Handle according to GMP and MSDS guidelines

  • Refer to the MSDS for complete safety, first-aid, and disposal instructions


Where to Buy Cetirizine Dihydrochloride?

Cetirizine Dihydrochloride Manufacturer

High-purity Cetirizine Dihydrochloride is manufactured under controlled pharmaceutical-grade processes to ensure stability, efficacy, and regulatory compliance.


Cetirizine Dihydrochloride Supplier & Distributor

ChemicalBull supplies pharma-grade Cetirizine Dihydrochloride in bulk packaging suitable for pharmaceutical manufacturers, research labs, and global distributors. Contact us today to request samples or place bulk orders.


MSDS for Cetirizine Dihydrochloride

The MSDS provides full details on handling precautions, exposure control, toxicology, and emergency measures for safe pharmaceutical use.

 

Frequently Asked Questions (FAQs)

  1. What is Cetirizine Dihydrochloride used for?

    It is used to treat allergic rhinitis, chronic urticaria, and other histamine-related conditions.

  2. Is Cetirizine Dihydrochloride safe for children?

    Yes, when formulated in pediatric syrups or dispersible tablets, it is safe under recommended dosing.

  3. Can Cetirizine be combined with decongestants?

    Yes, it is often combined with Pseudoephedrine in combination therapies for enhanced allergy relief.

  4. How is Cetirizine Dihydrochloride supplied?

    ChemicalBull supplies it in bulk containers with COA, MSDS, and full regulatory documentation.

  5. Does it cause drowsiness?

    As a second-generation antihistamine, Cetirizine Dihydrochloride has minimal sedative effects compared to first-generation antihistamines.