Carbidopa | 28860-95-9
Cas No :
28860-95-9
Form :
Powder
Molecular Weight :
244.24 G/Mol
Molecular Formula :
C10H14N2O4
Boiling Point :
420 °C
Melting Point :
214 °C
Flash Point :
210 °C
Solubility :
Soluble In Water
Description :
Overview of Carbidopa
Carbidopa is an essential pharmaceutical ingredient widely used in the treatment of Parkinson’s disease. It works by preventing the breakdown of Levodopa before it reaches the brain, allowing more Levodopa to convert into dopamine. This enhances the therapeutic effect while reducing side effects such as nausea and vomiting. Pharma manufacturers use Carbidopa in combination formulations where dosage stability, purity, and controlled release are critical for patient outcomes.
The standard and globally recognized name for this API is Carbidopa, used consistently in COA documents, DMF filings, regulatory submissions, and pharmacopoeias (USP/EP). It is a highly demanded material for neurological treatment formulations, especially when combined with Levodopa in immediate and extended-release tablets.
Applications of Carbidopa
Parkinson’s Disease Formulations
Carbidopa is used in combination therapies with Levodopa to improve dopamine levels in the brain. It is an essential component in Parkinson’s medicines where precision and purity are crucial.
Neurological Combination Drugs
Used in formulations paired with APIs like Entacapone and Rasagiline to enhance therapeutic response and patient compliance.
Controlled & Extended-Release Tablets
Carbidopa is incorporated into sustained-release dosage forms to maintain steady dopamine support throughout the day.
Movement Disorder Treatments
Applied in medicines that address tremors, rigidity, and slowness of movement associated with Parkinson’s and related disorders.
Safety & Handling Guidelines
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Store in light-protected, moisture-free containers
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Keep in a cool and controlled environment
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Use gloves, mask, and protective clothing while handling
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Refer to COA, MSDS, and GMP guidelines before processing
Where to Buy Carbidopa?
Carbidopa Manufacturer
Pharma-grade Carbidopa is produced under strict manufacturing controls ensuring high purity, stability, and compliance for neurological drug formulations.
Carbidopa Supplier & Distributor
ChemicalBull supplies high-quality Carbidopa with complete documentation, including COA, MSDS, and batch-level traceability for domestic and global customers.
MSDS for Carbidopa
The MSDS covers toxicity details, exposure prevention, safe handling methods, and emergency measures.
Frequently Asked Questions (FAQs)
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What is Carbidopa used for?
Carbidopa is used in Parkinson’s disease treatment, generally in combination with Levodopa. -
Can Carbidopa be used alone?
No, it is usually formulated with Levodopa for proper therapeutic action. -
Does Carbidopa require protection from light?
Yes, it should be stored in airtight, light-shielded conditions.