Candesartan Cilexetil | 145040-37-5

Cas No :

145040-37-5

Form :

Powder 

Molecular Weight :

610.7 G/Mol

Molecular Formula :

C33H34N6O6

Melting Point :

167 °C

Boiling Point :

500 °C

Solubility :

Sparingly Soluble In Water; Soluble In Methanol And Dimethyl Sulfoxide

Flash Point :

250 °C

Description :

Overview of Candesartan Cilexetil

 

Candesartan Cilexetil is a widely used antihypertensive medication in the Angiotensin II Receptor Blocker (ARB) class. It is used to treat high blood pressure and heart failure by relaxing blood vessels and improving blood circulation. In the pharmaceutical industry, it is processed into tablet formulations where stability, purity, and controlled therapeutic performance are essential. Industrial-scale production involves a precise, multi-step organic synthesis process that ensures high-quality output and minimal impurities.

The standard, globally accepted name for this API is Candesartan Cilexetil, which is consistently referenced in regulatory filings, COA documents, DMF submissions, and international pharmacopoeias. Due to its reliable therapeutic profile, it remains a high-demand active pharmaceutical ingredient for cardiovascular treatments.

 

Applications of Candesartan Cilexetil

 

Antihypertensive Drug Formulation

 

It is used as a first-line therapy for hypertension. Pharmaceutical manufacturers use it in tablets and fixed-dose combinations (FDCs). It is also compared with ARB APIs like Losartan Potassium, Irbesartan, and Olmesartan Medoxomil.

 

Heart Failure Treatment

 

Candesartan Cilexetil is used to reduce cardiac workload in heart failure patients. It is often combined with APIs such as Sacubitril and Metoprolol Succinate to enhance cardiovascular support.

 

Renal Protection in Diabetic Patients

 

It plays a protective role in diabetic nephropathy. Pharmaceutical companies use it in diabetic-friendly antihypertensive formulations similar to Telmisartan and Valsartan.

 

Safety & Handling Guidelines

 

  • Store in a dry, cool, and moisture-free environment

  • Keep away from direct heat and contamination

  • Use PPE: gloves, mask, lab coat

  • Review COA, MSDS, and regulatory documents before handling

 

Where to Buy Candesartan Cilexetil?

 

Candesartan Cilexetil Manufacturer

Pharma-grade Candesartan Cilexetil is manufactured under controlled conditions for cardiovascular formulations.

 

Candesartan Cilexetil Supplier & Distributor

ChemicalBull supplies Candesartan Cilexetil with COA, MSDS, and high-standard packaging suitable for domestic and international markets.

 

MSDS for Candesartan Cilexetil

 

MSDS includes safety hazards, exposure guidelines, stability, incompatibilities, and emergency procedures. Reviewing MSDS is essential prior to industrial handling.

 

Frequently Asked Questions (FAQs)

 

  1. Is Candesartan Cilexetil safe for pharmaceutical use?

    Yes, it is a globally accepted ARB API when used under pharmacopeial standards.

  2. Where is Candesartan Cilexetil used?

    It is used in antihypertensive, heart failure, and renal-protection formulations.

  3. Does Candesartan Cilexetil require moisture protection?

    Yes, it must be stored in sealed and dry conditions.