Amodiaquine Hydrochloride | 6398-98-7

Description :

Overview of Amodiaquine Hydrochloride

Amodiaquine Hydrochloride is a medical-grade antimalarial substance widely used to treat malaria. This is a synthesized derivative of 4-aminoquinoline that was developed to increase the effectiveness of antimalarials and clinical efficacy.

The pharmaceutical market, in particular, is Amodiaquine Hydroxide is regarded as a top choice due to its demonstrated effectiveness against Plasmodium strains as well as its use in combination antimalarial treatment. It is produced under controlled conditions to ensure high standards for purity, quality and safety standards.

As a pharmaceutical chemical, Amodiaquine Hydrochloride plays an important role in malaria treatment programs and public health initiatives.

Applications of Amodiaquine Hydrochloride

Antimalarial & Pharmaceutical Use

Amodiaquine Hydrochloride is primarily used for the treatment of uncomplicated malaria, often as part of combination therapy to reduce drug resistance. It acts by interfering with the parasite’s ability to detoxify haem, leading to parasite death.

In antimalarial formulations, it is often evaluated alongside Lumefantrine for combination therapy effectiveness.

Pharmaceutical Chemistry & Mechanism of Action

In pharmaceutical chemistry, Amodiaquine Hydrochloride belongs to the 4-aminoquinoline class. Its mechanism of action involves accumulation within the parasite’s food vacuole, disrupting haem polymerisation and inhibiting parasite growth.

It is also compared with related antimalarial agents such as Hydroxychloroquine Sulfate in pharmacological and formulation studies.

Clinical & Industrial Pharmaceutical Use

Amodiaquine Hydrochloride is used in tablet and oral dosage forms under medical supervision. It is widely utilised in hospital settings and large-scale pharmaceutical manufacturing for malaria control programs.

In malaria treatment planning, it may be referenced alongside classical antimalarials such as Quinine Sulphate.

Safety & Handling Guidelines

• Keep in a cool, dry, and well-ventilated location
• Make sure containers are tightly sealed and clearly labeled
• Avoid breathing in dust during handling
• Avoid direct contact with skin and eyes
• Use protective gloves, goggles, and pharmaceutical-grade clothing
• Handle under controlled pharmaceutical manufacturing conditions
• Dispose of waste according to regulatory guidelines
  
  
  

Where to Buy Amodiaquine Hydrochloride?

Amodiaquine Hydrochloride Manufacturer

Amodiaquine Hydrochloride is manufactured for pharmaceutical applications where high purity, consistent potency, and compliance with antimalarial drug standards are essential.

Amodiaquine Hydrochloride Supplier & Distributor

Amodiaquine Hydrochloride is supplied in pharmaceutical-grade packaging for formulation manufacturers and healthcare institutions. As a pharmaceutical chemicals supplier and distributor, Chemicalbull Pvt. Ltd. supports customers with reliable sourcing and standard documentation.

MSDS for Amodiaquine Hydrochloride

The MSDS for Amodiaquine Hydrochloride provides detailed information on hazards, safe handling practices, storage conditions, exposure controls, first-aid measures, and emergency response procedures. Always review the MSDS before pharmaceutical use.

Frequently Asked Questions (FAQs)

1. What is Amodiaquine Hydrochloride?
   

   Amodiaquine Hydrochloride is an antimalarial pharmaceutical compound used to treat malaria infections caused by Plasmodium parasites.
   
   

2. What is the chemical formula of Amodiaquine Hydrochloride?
   

   The chemical formula of Amodiaquine Hydrochloride is C₂₀H₂₂ClN₃O·HCl.
   
   

3. What is the structure of Amodiaquine Hydrochloride?
   

   Amodiaquine hydrochloride structure consists of a 4-aminoquinoline core with substituted aromatic and amino side chains, contributing to its antimalarial activity.
   
   

4. What is the use of Amodiaquine Hydrochloride?
   

   Amodiaquine Hydrochloride is used in the treatment of uncomplicated malaria, often in combination therapies to improve effectiveness and reduce resistance.
   
   

5. How is Amodiaquine Hydrochloride synthesised?
   

   Amodiaquine hydrochloride synthesis involves multi-step quinoline derivatisation followed by salt formation under controlled pharmaceutical manufacturing conditions.