5-Chlorothiophene-2-Carboxylic Acid | 24065-33-6

Description :

Overview of 5-Chlorothiophene-2-Carboxylic Acid

5-Chlorothiophene-2-Carboxylic Acid is an industrial heterocyclic intermediate widely used in pharmaceutical, agrochemical, and specialty chemical manufacturing. It is composed of a thiophene ring replaced by the chlorine atom, as well as an acid group that is carboxylic, which makes it extremely reactive when it comes to coupling, substitution, and esterification processes.

As an industrial chemical, 5-Chlorothiophene-2-Carboxylic Acid serves as a key building block in the synthesis of active pharmaceutical intermediates (APIs), thiophene derivatives, and advanced organic compounds. Its halogenated heterocyclic structure makes it particularly valuable in fine chemical production and R&D applications.

Applications of 5-Chlorothiophene-2-Carboxylic Acid

Pharmaceutical Intermediate Manufacturing

5-Chlorothiophene-2-Carboxylic Acid is widely used in the synthesis of pharmaceutical intermediates and heterocyclic drug candidates. The chloro group enables further functionalization via substitution reactions.

It may be processed alongside Thionyl Chloride, Triethylamine, and Acetonitrile in controlled industrial synthesis systems.

Agrochemical & Crop Protection Chemistry

This compound serves as an intermediate in agrochemical production, particularly in the development of thiophene-based active ingredients.

In industrial processing, it may be used with Potassium Carbonate, Dimethylformamide, and Methanol for derivative formation.

Coupling & Cross-Coupling Reactions

Due to the presence of a chloro-substituted heterocycle, 5-Chlorothiophene-2-Carboxylic Acid is suitable for palladium-catalysed cross-coupling reactions such as Suzuki and Heck reactions.

Fine Chemical & Specialty Derivative Production

The compound is used in the preparation of thiophene-based specialty chemicals, esters, and amides for advanced material and chemical applications.

Safety & Handling Guidelines

• Store in a cool, dry, and well-ventilated area
• Keep containers tightly sealed and properly labelled
• Avoid inhalation of dust
• Prevent contact with skin and eyes
• Wear protective gloves or goggles, and wear appropriate industrial clothes
• Handle in controlled industrial conditions
• Waste disposal is governed by the requirements of regulatory compliance

Always consult the MSDS before industrial handling.

Where to Buy 5-Chlorothiophene-2-Carboxylic Acid?

5-Chlorothiophene-2-Carboxylic Acid Manufacturer

5-Chlorothiophene-2-Carboxylic Acid is manufactured under controlled industrial standards to ensure consistent purity and performance for pharmaceutical and fine chemical applications.

5-Chlorothiophene-2-Carboxylic Acid Supplier & Distributor

5-Chlorothiophene-2-Carboxylic Acid is available in bulk and industrial packaging formats. Buy 5-Chlorothiophene-2-Carboxylic Acid from Chemicalbull Pvt. Ltd., a trusted industrial chemicals supplier and distributor in India, ensuring reliable sourcing and compliant logistics support.

MSDS for 5-Chlorothiophene-2-Carboxylic Acid

The MSDS for 5-Chlorothiophene-2-Carboxylic Acid provides detailed information on hazard identification, safe handling practices, storage requirements, exposure controls, and emergency response measures. It is required to be read prior to the use of the product.

Frequently Asked Questions (FAQs)

1. What is the formula of 5-Chlorothiophene-2-Carboxylic Acid?
   

   The chemical formula of 5-Chlorothiophene-2-Carboxylic Acid is C₅H₃ClO₂S.
   
   

2. What is 5-Chlorothiophene-2-Carboxylic Acid used for?
   

   It is used as a pharmaceutical and agrochemical intermediate, particularly in heterocyclic synthesis and cross-coupling reactions.
   
   

3. How is 5-Chlorothiophene-2-Carboxylic Acid synthesised?
   

   5-Chlorothiophene-2-Carboxylic Acid synthesis typically involves controlled chlorination of thiophene derivatives or carboxylation reactions under regulated industrial conditions.