4-chlorophenacyl Bromide | 536-38-9
Cas No :
536-38-9
Form :
Solid
Molecular Weight :
233.49 G/mol
Molecular Formula :
C8H6BRCLO
Boiling Point :
210 °c
Melting Point :
60 °c
Flash Point :
110 °c
Solubility :
Sparingly Soluble In Water; Soluble In Acetone, Ethanol, Dichloromethane
Description :
Overview of 4-Chlorophenacyl Bromide
4-Chlorophenacyl Bromide is a reactive α-haloketone used as a pharmaceutical intermediate, reagent in organic synthesis, and alkylating agent. Known for its dual electrophilic character from both carbonyl and α-bromine, excellent reactivity with nucleophiles, and use in various synthetic transformations, 4-Chlorophenacyl Bromide is widely used in pharmaceutical manufacturing, heterocyclic synthesis, and specialty chemical production.
This compound appears as a white to off-white crystalline solid. Its structure, combining aromatic chloride, ketone, and α-bromide, provides unique reactivity patterns.
Related products include Phenacyl Bromide, Boron Tribromide, and other α-haloketones used in pharmaceutical synthesis and organic chemistry.
Applications of 4-Chlorophenacyl Bromide
Pharmaceutical Synthesis
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Used in synthesizing pharmaceutical intermediates
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Applied in preparing drug candidates
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Used in manufacturing active pharmaceutical ingredients
Organic Synthesis
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Used in alkylation reactions
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Applied in synthesizing imidazoles
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Used in preparing thiazoles
Analytical Chemistry
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Used as a derivatizing agent for carboxylic acids
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Applied in HPLC analysis
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Used in developing analytical methods
Safety & Handling Guidelines
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LACHRYMATORY—causes severe eye irritation and tearing
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CORROSIVE—causes burns
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Avoid inhalation of dust and vapors
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Use gloves, goggles, a face shield, and protective clothing
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Handle in a well-ventilated fume hood
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Store in tightly closed containers in a cool, dry place
Where to Buy 4-Chlorophenacyl Bromide?
4-Chlorophenacyl Bromide Manufacturer
ChemicalBull supplies high-purity 4-Chlorophenacyl Bromide for pharmaceutical and research applications.
4-Chlorophenacyl Bromide Supplier & Distributor
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Available in controlled quantities for pharmaceutical and research use
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High-purity grades (97%, 98%, 99%)
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COA, MSDS, and comprehensive safety documentation provided
MSDS
Includes comprehensive lachrymatory and reactivity warnings and handling protocols.
Frequently Asked Questions (FAQs)
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What is the 4-chlorophenacyl bromide formula?
Molecular formula: C₈H₆BrClO with molecular weight 233.49 g/mol. -
What is the 4-chlorophenacyl bromide synthesis?
Synthesized by bromination of 4-chloroacetophenone using bromine or brominating agents. -
What is 4-Chlorophenacyl Bromide used for?
Used in pharmaceutical synthesis, heterocyclic compound preparation, and as a derivatizing agent in analytical chemistry.
ChemicalBull supplies 4-chlorophenacyl Bromide across India, serving customers in Andhra Pradesh, Arunachal Pradesh, Assam, Bihar, Chhattisgarh, Goa, Gujarat, Haryana, Himachal Pradesh, Jharkhand, Karnataka, Kerala, Madhya Pradesh, Maharashtra, Manipur, Meghalaya, Mizoram, Nagaland, Odisha, Punjab, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Uttar Pradesh, Uttarakhand, and West Bengal, as well as the Union Territories of Andaman & Nicobar Islands, Chandigarh, Dadra & Nagar Haveli and Daman & Diu, Delhi, Jammu & Kashmir, Ladakh, Lakshadweep, and Puducherry. We serve pharmaceutical, chemical, research, academic, laboratory, manufacturing, and industrial customers with reliable nationwide delivery.