4-Chlorophenacyl Bromide
Description :
Overview of 4-Chlorophenacyl Bromide
4-Chlorophenacyl Bromide is a reactive α-haloketone used as a pharmaceutical intermediate, reagent in organic synthesis, and alkylating agent. Known for its dual electrophilic character from both carbonyl and α-bromine, excellent reactivity with nucleophiles, and use in various synthetic transformations, 4-Chlorophenacyl Bromide is widely used in pharmaceutical manufacturing, heterocyclic synthesis, and specialty chemical production.
This compound appears as a white to off-white crystalline solid. Its structure, combining aromatic chloride, ketone, and α-bromide, provides unique reactivity patterns.
Related products include Phenacyl Bromide, Boron Tribromide, and other α-haloketones used in pharmaceutical synthesis and organic chemistry.
Applications of 4-Chlorophenacyl Bromide
Pharmaceutical Synthesis
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Used in synthesizing pharmaceutical intermediates
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Applied in preparing drug candidates
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Used in manufacturing active pharmaceutical ingredients
Organic Synthesis
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Used in alkylation reactions
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Applied in synthesizing imidazoles
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Used in preparing thiazoles
Analytical Chemistry
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Used as a derivatizing agent for carboxylic acids
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Applied in HPLC analysis
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Used in developing analytical methods
Safety & Handling Guidelines
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LACHRYMATORY—causes severe eye irritation and tearing
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CORROSIVE—causes burns
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Avoid inhalation of dust and vapors
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Use gloves, goggles, a face shield, and protective clothing
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Handle in a well-ventilated fume hood
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Store in tightly closed containers in a cool, dry place
Where to Buy 4-Chlorophenacyl Bromide?
4-Chlorophenacyl Bromide Manufacturer
ChemicalBull supplies high-purity 4-Chlorophenacyl Bromide for pharmaceutical and research applications.
4-Chlorophenacyl Bromide Supplier & Distributor
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Available in controlled quantities for pharmaceutical and research use
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High-purity grades (97%, 98%, 99%)
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COA, MSDS, and comprehensive safety documentation provided
MSDS
Includes comprehensive lachrymatory and reactivity warnings and handling protocols.
Frequently Asked Questions (FAQs)
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What is the 4-chlorophenacyl bromide formula?
Molecular formula: C₈H₆BrClO with molecular weight 233.49 g/mol. -
What is the 4-chlorophenacyl bromide synthesis?
Synthesized by bromination of 4-chloroacetophenone using bromine or brominating agents. -
What is 4-Chlorophenacyl Bromide used for?
Used in pharmaceutical synthesis, heterocyclic compound preparation, and as a derivatizing agent in analytical chemistry.
