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4-Chlorobenzenesulfonyl Chloride

4-Chlorobenzenesulfonyl Chloride | 98-60-2

Cas No :

98-60-2

Form :

Solid

Molecular Weight :

211.06 

Molecular Formula :

C6H4CL2O2S

Boiling Point :

108 °C

Melting Point :

50 - 52 °C

Flash Point :

108 °C

Description :

Overview of 4-Chlorobenzenesulfonyl Chloride

 

4-Chlorobenzenesulfonyl Chloride (also known as p-chlorobenzenesulfonyl chloride) is a white to off-white crystalline solid sulfonyl chloride, highly reactive for sulfonamide and sulfonate ester formation.

Chemical Formula C6H4Cl2O2S

Molecular Weight: 211.07 grams/mol.

CAS Number 98-60-2.

Specific properties: Strong electrophile sensitive to moisture, it is used for nucleophilic acyl substitutions.

 

 

Applications of 4-Chlorobenzenesulfonyl Chloride

 

Pharmaceutical and Agrochemical Intermediates

 

  • The key reagent for making sulfonamides, sulfonylureas, as well as bioactive substances

  • Protects the amines and forms sulfonate ester during multi-step synthesis

 

Dye and Chemical Industry

 

  • Intermediate for dyes and special chemicals, pigments and other dyes

  • Relative to Halogenated reactions or safeguards using Boron Tribromide for selective transformations

 

 

Safety and Handling Guidelines

 

  • Wear protective goggles, gloves, and appropriate clothing (corrosive, lachrymatory)

  • Avoid contact with moisture (reacts to form HCl)

  • Use only in a well-ventilated fume hood

  • Store in sealed containers under dry conditions

  • Follow MSDS guidelines and standard safety protocols (corrosive, toxic)

 

 

Where to Buy 4-Chlorobenzenesulfonyl Chloride

 

4-Chlorobenzenesulfonyl Chloride Manufacturer

 

  • High-purity suppliers for pharma and fine chemical grades

 

4-Chlorobenzenesulfonyl Chloride Supplier & Distributor

 

  • Bulk supply with COA, TDS & MSDS available

 

 

4-Chlorobenzenesulfonyl Chloride MSDS

 

Provides details on hazards, handling, storage, and emergency precautions

 

 

Frequently Asked Questions (FAQs)

 

  1. What is the molecular weight and CAS of 4-Chlorobenzenesulfonyl chloride?

    Molecular weight 211.07 g/mol, CAS 98-60-2; formula C6H4Cl2O2S.

  2. What are the uses of 4-Chlorobenzenesulfonyl chloride?

    As a sulfonylating agent in the synthesis of sulfonamides, pharmaceuticals, agrochemicals, and dyes.

  3. How is 4-Chlorobenzenesulfonyl chloride synthesised?

    Typically, it is achieved by chlorosulfonation of chlorobenzene or reaction of sulfonic acid with thionyl chloride.