4-Bromo-2,2-Diphenylacetonitrile | 39186-58-8
Cas No :
39186-58-8
Form :
Solid
Molecular Weight :
271.12 G/Mol
Molecular Formula :
C16H14BRN
Boiling Point :
320 °C
Melting Point :
135 °C
Flash Point :
140 °C
Solubility :
Soluble In Organic Solvents (Chloroform, Acetone, Ethyl Acetate); Insoluble In Water
Description :
Overview of 4-Bromo-2,2-Diphenylacetonitrile
4-Bromo-2,2-Diphenylacetonitrile (CAS: 5581-06-8) is a halogenated aromatic nitrile compound widely used in organic synthesis, pharmaceutical intermediates, specialty chemicals, and fine chemical manufacturing. It appears as a pale yellow crystalline solid and is valued for its reactivity in nucleophilic substitution, condensation, and coupling reactions.
This compound serves as a key building block for complex organic molecules, active pharmaceutical intermediates, and specialty chemical reagents. Its bromine functional group and stabilized diphenyl structure make it suitable for high-performance synthesis and industrial-scale chemical reactions.
In industrial applications, related brominated nitriles such as 2-Bromo-2-phenylacetonitrile, 4-Bromobenzonitrile, and 1-Bromo-3-Chloropropane are also used for pharmaceutical intermediates, agrochemical synthesis, and specialty organic reactions.
Applications of 4-Bromo-2,2-Diphenylacetonitrile
Pharmaceutical & Fine Chemical Synthesis
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Used as an intermediate in the synthesis of active pharmaceutical ingredients (APIs)
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Supports construction of bioactive aromatic and heterocyclic molecules
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Applied in medicinal chemistry and specialty chemical research
Organic Synthesis & Specialty Chemicals
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Serves as a building block for nucleophilic substitution and condensation reactions
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Suitable for preparing intermediates in dyes, polymers, and advanced organics
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Applied in academic and industrial R&D laboratories
Agrochemical Applications
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Functions as a key intermediate in the synthesis of brominated agrochemicals
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Supports production of herbicides, fungicides, and pesticide intermediates
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Useful for industrial-scale specialty chemical manufacturing
Laboratory & Research Applications
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Used in chemical research and organic synthesis studies
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Supports development of novel chemical scaffolds and intermediates
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Applied in functionalization of aromatic and nitrile-containing compounds
Safety & Handling Guidelines
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Avoid direct contact with skin, eyes, and clothing
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Use gloves, goggles, and protective clothing
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Handle in well-ventilated areas or fume hoods
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Store in tightly sealed containers away from heat, moisture, and oxidizers
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Follow COA and MSDS instructions carefully
Where to Buy 4-Bromo-2,2-Diphenylacetonitrile?
4-Bromo-2,2-Diphenylacetonitrile Manufacturer
ChemicalBull supplies high-purity 4-Bromo-2,2-Diphenylacetonitrile suitable for pharmaceutical synthesis, organic intermediates, and specialty chemical manufacturing.
4-Bromo-2,2-Diphenylacetonitrile Supplier & Distributor
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Available in bulk and laboratory-scale packaging
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Ideal for organic synthesis, fine chemical production, and R&D applications
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COA, MSDS, and detailed technical specifications provided
4-Bromo-2,2-Diphenylacetonitrile MSDS
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May cause skin, eye, and respiratory irritation
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Flammable under certain conditions—avoid sparks and heat
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Avoid inhalation of dust or vapors
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Store in cool, dry, ventilated environments
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Refer to full MSDS for spill response and emergency procedures
Frequently Asked Questions (FAQs)
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What is the molecular formula of 4-Bromo-2,2-Diphenylacetonitrile?
Molecular Formula: C₁₅H₁₂BrN
Molecular Weight: 271.17 g/mol -
What is 4-Bromo-2,2-Diphenylacetonitrile used for?
Used as a building block for pharmaceutical intermediates, organic synthesis, and specialty chemical manufacturing. -
Which industries use 4-Bromo-2,2-Diphenylacetonitrile?
Common industries include pharmaceuticals, fine chemicals, agrochemical intermediates, and specialty chemical R&D. -
Is 4-Bromo-2,2-Diphenylacetonitrile hazardous?
Yes. It may cause irritation to skin, eyes, and respiratory system, and should be handled using proper PPE following MSDS guidelines. -
Why is it important in organic synthesis?
Its brominated aromatic nitrile structure allows for efficient nucleophilic substitution and condensation reactions, making it valuable for high-performance chemical and pharmaceutical synthesis.