2-Fluorobenzyl Bromide | 446-48-0
Cas No :
446-48-0
Synonyms :
Form :
Liquid
Molecular Weight :
189.02 g/mol
Molecular Formula :
C7H6BRF
Boiling Point :
210 °C
Melting Point :
-15 °C
Flash Point :
82 °C
Solubility :
Soluble in organic solvents, insoluble in water
Description :
2-Fluorobenzyl Bromide Supplier & Distributor In India
ChemicalBull is a trusted 2-Fluorobenzyl Bromide supplier, distributor, and exporter in India, supporting sourcing for pharmaceutical intermediate manufacturers, fine chemical companies, organic synthesis units, research laboratories, chemical distributors, wholesalers, and global B2B buyers.
2-Fluorobenzyl Bromide, also known as o-Fluorobenzyl Bromide or alpha-Bromo-2-fluorotoluene, is a fluorinated organic compound with CAS number 446-48-0. It is used as an alkylating reagent and building block for preparing fluorinated benzyl derivatives and pharmaceutical intermediates.
Contact ChemicalBull for a 2-Fluorobenzyl Bromide Quote — Share your required quantity, purity, packing size, and delivery location to request bulk pricing and supply details.
Overview of 2-Fluorobenzyl Bromide
2-Fluorobenzyl Bromide has the molecular formula C7H6BrF and a molecular weight of approximately 189.03 g/mol. Its structure contains a bromomethyl group attached to a benzene ring, with fluorine in the adjacent ortho position.
The compound is generally supplied as a clear liquid, with appearance ranging from colourless to light yellow or light orange. Its reactive benzyl bromide group provides a site for introducing a 2-fluorobenzyl group into suitable target molecules.
Buyers should confirm assay, isomer identity, water content, impurity profile, appearance, packaging, and storage requirements before procurement. Review the offered specification and batch COA against the intended synthesis process.
Applications of 2-Fluorobenzyl Bromide
Pharmaceutical Intermediate Synthesis
2-Fluorobenzyl Bromide has been used in the synthesis of prasugrel. Pharmaceutical intermediate manufacturers should assess the supplied grade against their approved synthesis route, assay requirements, and impurity limits.
Alkylation Reactions
The compound acts as an alkylating reagent in suitable organic synthesis reactions. Its bromomethyl group enables the introduction of a 2-fluorobenzyl group through nucleophilic substitution.
Heterocyclic Compound Preparation
2-Fluorobenzyl Bromide has been used in the preparation of substituted pyrrolopyrimidines and alkylated imidazolopyrimidinones. These applications support heterocyclic synthesis and medicinal chemistry research.
Fluorinated Benzyl Derivatives
Fine chemical developers can use 2-Fluorobenzyl Bromide in selected routes to fluorinated benzyl ethers and nitrogen-containing derivatives. Reaction suitability depends on the nucleophile, solvent, base, and target structure.
Laboratory & Research Use
Research laboratories use 2-Fluorobenzyl Bromide for synthetic route development, reaction screening, and fluorinated compound preparation. Researchers should select a grade suitable for their experimental and analytical requirements.
2-Fluorobenzyl Bromide Supply Support For Industrial Buyers
ChemicalBull supports 2-Fluorobenzyl Bromide sourcing for pharmaceutical intermediate companies, fine chemical manufacturers, organic synthesis units, laboratories, distributors, wholesalers, and export customers.
As a supplier, distributor, and exporter, ChemicalBull assists buyers with specification enquiries, packing options, quantity requirements, and documentation requests. Buyers can request COA, TDS, SDS or MSDS, and applicable export documents for the offered grade.
Why Choose ChemicalBull For 2-Fluorobenzyl Bromide?
ChemicalBull helps B2B buyers coordinate 2-Fluorobenzyl Bromide sourcing according to their required specification, order quantity, packaging needs, and delivery schedule.
Our team supports bulk quotation enquiries, document assistance, domestic dispatch coordination, export requirements, and repeat procurement planning. Share your required assay and impurity limits so the offered material can be reviewed before order confirmation.
2-Fluorobenzyl Bromide MSDS & Handling
2-Fluorobenzyl Bromide can cause severe skin burns, eye damage, and respiratory irritation. Avoid direct contact and breathing vapour or mist. Use suitable chemical-resistant gloves, protective clothing, eye and face protection, and effective local exhaust ventilation.
Keep containers tightly closed and protect the material from moisture. Follow the supplied SDS for storage temperature, any inert-gas requirements, compatible containers, and incompatible chemicals. Keep away from heat and ignition sources. Review the latest SDS or MSDS for first aid, spill response, exposure controls, and disposal instructions before handling.
Related Products
Buyers sourcing 2-Fluorobenzyl Bromide may also enquire about related benzyl compounds and fluorinated synthesis building blocks from ChemicalBull.
Request a Quote for 2-Fluorobenzyl Bromide
Need 2-Fluorobenzyl Bromide CAS 446-48-0 for pharmaceutical intermediate synthesis, alkylation reactions, fluorinated derivatives, or laboratory research?
Send your required quantity, purity, impurity limits, packing size, application, delivery location, and document needs to ChemicalBull. Our team will confirm the offered specification, current availability, bulk pricing, and supply options for domestic or export orders.
Frequently Asked Questions
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What is 2-Fluorobenzyl Bromide?
2-Fluorobenzyl Bromide is a fluorinated organic compound also known as o-Fluorobenzyl Bromide or alpha-Bromo-2-fluorotoluene. It is used as an alkylating reagent and synthesis building block. -
What is the CAS number of 2-Fluorobenzyl Bromide?
The CAS number is 446-48-0. Its molecular formula is C7H6BrF, and its molecular weight is approximately 189.03 g/mol. -
What is 2-Fluorobenzyl Bromide used for?
It is used in selected pharmaceutical synthesis routes, including prasugrel synthesis, alkylation reactions, heterocyclic compound preparation, and fluorinated benzyl derivative development. -
Who supplies 2-Fluorobenzyl Bromide in India?
ChemicalBull supports 2-Fluorobenzyl Bromide supply in India for chemical manufacturers, pharmaceutical intermediate companies, laboratories, distributors, and bulk buyers. -
Can I request bulk pricing and 2-Fluorobenzyl Bromide MSDS?
Yes. Share your quantity, specification, and delivery location with ChemicalBull to request bulk pricing and 2-Fluorobenzyl Bromide CAS 446-48-0 MSDS or SDS. COA, TDS, and other documents can be requested for the offered grade.
ChemicalBull supplies 2-Fluorobenzyl Bromide across India, serving customers in Andhra Pradesh, Arunachal Pradesh, Assam, Bihar, Chhattisgarh, Goa, Gujarat, Haryana, Himachal Pradesh, Jharkhand, Karnataka, Kerala, Madhya Pradesh, Maharashtra, Manipur, Meghalaya, Mizoram, Nagaland, Odisha, Punjab, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Uttar Pradesh, Uttarakhand, and West Bengal, as well as the Union Territories of Andaman & Nicobar Islands, Chandigarh, Dadra & Nagar Haveli and Daman & Diu, Delhi, Jammu & Kashmir, Ladakh, Lakshadweep, and Puducherry. We serve pharmaceutical, chemical, research, academic, laboratory, manufacturing, and industrial customers with reliable nationwide delivery.