1-bromo-4-fluorobenzene | 460-00-4

Description :

Overview of 1-Bromo-4-Fluorobenzene

1-Bromo-4-Fluorobenzene (CAS: 460-00-4) is a halogenated aromatic compound widely used as an intermediate in pharmaceuticals, agrochemicals, and specialty chemical synthesis. It appears as a colorless to pale yellow liquid with excellent chemical stability and reactivity toward nucleophilic substitution and cross-coupling reactions.

Valued for its bromine and fluorine substituents, it is frequently used in Suzuki, Heck, and other palladium-catalyzed reactions to produce complex aromatic derivatives. Its applications include the preparation of fine chemicals, active pharmaceutical ingredients (APIs), and advanced materials.

Related products available on ChemicalBull: 1-Bromobenzene, 4-Fluorobenzaldehyde, Bromobenzene derivatives – commonly used in halogenated intermediates, pharmaceutical synthesis, and organic chemistry research.

Applications of 1-Bromo-4-Fluorobenzene

Pharmaceutical Intermediates

• Key intermediate for API synthesis

• Used in the preparation of halogenated drug molecules

• Applied in medicinal chemistry research and pharmaceutical R&D

Organic Synthesis & Cross-Coupling Reactions

• Suitable for Suzuki, Heck, and Sonogashira coupling

• Used to produce substituted aromatic compounds

• Applied in specialty chemical and fine chemical manufacturing

Agrochemical & Specialty Chemicals

• Intermediate in the synthesis of herbicides, pesticides, and fungicides

• Supports production of halogenated functional compounds

• Used in research and industrial development of agrochemical derivatives

Laboratory & Analytical Applications

• Used in small-scale lab reactions for developing novel molecules

• Supports academic and industrial chemical research

• Applied in the preparation of halogenated aromatic standards

Safety & Handling Guidelines

• Flammable and reactive with strong bases

• Wear gloves, goggles, and protective clothing

• Handle in a well-ventilated area or fume hood

• Store in tightly sealed containers away from heat and oxidizing agents

• Follow COA and MSDS guidelines strictly

Where to Buy 1-Bromo-4-Fluorobenzene?

1-Bromo-4-Fluorobenzene Manufacturer

ChemicalBull supplies high-purity 1-Bromo-4-Fluorobenzene for pharmaceutical, agrochemical, and fine chemical synthesis.

1-Bromo-4-Fluorobenzene Supplier & Distributor

• Available in bulk and laboratory-scale packaging

• Suitable for cross-coupling reactions, API synthesis, and specialty chemical manufacturing

• COA, MSDS, and technical specifications provided

1-Bromo-4-Fluorobenzene MSDS

• Flammable liquid; may cause skin and eye irritation

• Use PPE and avoid inhalation of vapors

• Handle in ventilated areas; prevent exposure to sparks or heat

• Store away from acids, oxidizers, and incompatible substances

• Refer to full MSDS for detailed handling, spill control, and emergency procedures

Frequently Asked Questions (FAQs)

1. What is the molecular formula of 1-Bromo-4-Fluorobenzene?

   Molecular Formula: C₆H₄BrF
   Molecular Weight: 157.00 g/mol
   
   

2. What is 1-Bromo-4-Fluorobenzene used for?

   Used as a halogenated intermediate in pharmaceuticals, agrochemicals, organic synthesis, and cross-coupling reactions.
   
   

3. Is 1-Bromo-4-Fluorobenzene hazardous?

   Flammable and irritant; handle with proper PPE and follow MSDS instructions.

ChemicalBull supplies 1-bromo-4-fluorobenzene across India, serving customers in Andhra Pradesh, Arunachal Pradesh, Assam, Bihar, Chhattisgarh, Goa, Gujarat, Haryana, Himachal Pradesh, Jharkhand, Karnataka, Kerala, Madhya Pradesh, Maharashtra, Manipur, Meghalaya, Mizoram, Nagaland, Odisha, Punjab, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Uttar Pradesh, Uttarakhand, and West Bengal, as well as the Union Territories of Andaman & Nicobar Islands, Chandigarh, Dadra & Nagar Haveli and Daman & Diu, Delhi, Jammu & Kashmir, Ladakh, Lakshadweep, and Puducherry. We serve pharmaceutical, chemical, research, academic, laboratory, manufacturing, and industrial customers with reliable nationwide delivery.