1,2,4-Triazole | 288-88-0

Cas No :

288-88-0

Synonyms :

Form :

Solid

Molecular Weight :

69.07 

Molecular Formula :

C2H3N3

Melting Point :

119 - 121 °C

Boiling Point :

260 °C

Solubility :

Dmso (Slightly), Methanol (Slightly)

Flash Point :

170 °C

Description :

Overview of 1,2,4-Triazole

1,2,4-Triazole is a nitrogen-rich heterocyclic organic compound containing three nitrogen atoms within a five-membered ring. It appears as a white to off-white crystalline solid and is highly valued as a core intermediate in agrochemicals, pharmaceuticals, and speciality chemicals.

In simple terms, 1,2,4-Triazole is a key “chemical backbone” used to build many active compounds. Because of its strong nitrogen structure, it helps improve biological activity, stability, and effectiveness in final products such as fungicides and medicines.

Many widely used agricultural fungicides and pharmaceutical compounds are derived from 1,2,4-Triazole chemistry. It is often processed together with intermediates like 2-Chlorobenzonitrile and 2,6-Difluorobenzamide to create advanced performance molecules.

 

Applications of 1,2,4-Triazole

Agrochemical & Fungicide Manufacturing

1,2,4-Triazole is most commonly used as a key intermediate in triazole-based fungicides, which are widely applied in agriculture to protect crops from fungal diseases.

These fungicides help control rusts, mildews, and leaf spot diseases in crops such as cereals, fruits, and vegetables. Due to its strong antifungal properties, triazole chemistry plays a critical role in modern crop protection systems.

 

Pharmaceutical Intermediates

In the pharmaceutical industry, 1,2,4-Triazole is used to manufacture antifungal drugs, antibacterial agents, and other therapeutic compounds. Its nitrogen-rich ring allows easy modification to create molecules with improved bioavailability and efficacy.

It is frequently used alongside intermediates such as 2-Chlorobenzonitrile during multi-step pharmaceutical synthesis.

 

Research & Laboratory Use

In research laboratories, 1,2,4-Triazole is used as a reference compound and building block for developing new agrochemical and pharmaceutical molecules. It is widely studied in heterocyclic chemistry and medicinal research.

 

Safety & Handling Guidelines

  • Store in a cool, dry, and well-ventilated place

  • Keep containers tightly sealed

  • Avoid dust formation and inhalation

  • Use protective gloves, goggles, and appropriate clothing

  • Follow standard industrial and laboratory safety procedures

Always handle according to MSDS and regulatory guidelines.

 

Where to Buy 1,2,4-Triazole?

1,2,4-Triazole Manufacturer

ChemicalBull manufactures and supplies high-quality 1,2,4-Triazole suitable for agrochemical, pharmaceutical, and speciality chemical applications, ensuring consistent purity and performance. As a trusted chemical supplier and distributor, we provide a wide range of agrochemical raw materials and crop protection chemicals. Our supply network supports manufacturers with dependable sourcing, consistent quality, and scalable bulk supply solutions.

 

1,2,4-Triazole Supplier & Distributor

As a trusted supplier and distributor, we offer:

  • Bulk and customised packaging options

  • Reliable domestic and international supply

  • Quality documentation including COA and MSDS

Visit our Home Page to connect with a chemical supplier, trusted distributor, and industrial chemicals manufacturer serving global markets.

 

1,2,4-Triazole MSDS

The Material Safety Data Sheet (MSDS) for 1,2,4-Triazole provides detailed information on:

  • Handling and storage requirements

  • Exposure controls and PPE

  • First-aid and emergency measures

Always review the MSDS before use in manufacturing or laboratory environments.

 

Frequently Asked Questions (FAQs)

  1. What is 1,2,4-Triazole used for?

    It is used mainly as an intermediate in fungicides, pharmaceuticals, and specialty chemicals.

  2. Is 1,2,4-Triazole a fungicide itself?

    No, it is not directly applied; it is used to manufacture triazole-based fungicides.

  3. Is 1,2,4-Triazole used in medicines?

    Yes, it is a core structure in many antifungal and antibacterial pharmaceutical compounds.

  4. Is 1,2,4-Triazole hazardous?

    It should be handled carefully following MSDS and industrial safety guidelines.

  5. Where can I buy 1,2,4-Triazole?

    You can source it from ChemicalBull, a reliable manufacturer and supplier of industrial and specialty chemicals.