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Phosphodiesterase Inhibitors

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A class of medications known as phosphodiesterase inhibitors (PDE inhibitors) prevents phosphodiesterase enzymes from acting, namely phosphodiesterase type 5 (PDE5). Cyclic nucleotides, such as cyclic guanosine monophosphate (cGMP) and cyclic adenosine monophosphate (cAMP), are broken down by these enzymes. These medications increase cAMP and cGMP levels by blocking PDE activity, ...

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