A class of drugs known as keratolytic agents is used in dermatology and skincare to treat disorders like psoriasis, corns, calluses, and acne that are characterized by excessive keratinization. These substances function by loosening and relaxing the stratum corneum, the skin's outermost layer, and by encouraging the exfoliation of dead skin cells. For people with skin diseases that cause thickened, rough, or scaly skin, this can be extremely helpful in improving the appearance and texture of the skin. Salicylic acid is one of the most often employed keratolytic substances. Salicylic acid, a beta hydroxy acid (BHA), exfoliates the skin by getting inside the pores and severing the connections between skin cells. It effectively treats acne by clearing up pores and halting the growth of new lesions. Urea is another often used keratolytic substance. When administered topically, urea, a naturally occurring component of the skin's moisture-retention system, aids in hydrating the skin and speeds up the exfoliation process. The skin conditions ichthyosis and xerosis, which are characterized by dry, rough skin, are frequently treated with urea. Alpha hydroxy acid (AHA) glycolic acid is also used as a keratolytic agent. It promotes a smoother and more luminous complexion by removing the intercellular glue that keeps dead skin cells together. Chemical peels and skincare treatments meant to enhance skin texture and lessen the look of fine lines and wrinkles frequently contain glycolic acid. In addition to these acids, other keratolytic substances include benzoyl peroxide, which is used to treat acne by both exfoliating the skin and inhibiting the growth of acne-causing bacteria, and lactic acid, another AHA with exfoliating capabilities. Keratolytic agents should only be used sparingly because overuse or misuse can cause skin irritation and other negative side effects. To get the best benefits and reduce any potential side effects, it is crucial to adhere to a healthcare provider's or dermatologist's advice while incorporating these agents into your skincare routine.
