A neurodegenerative condition called Huntington's disease (HD) damages the nerve cells in the brain, gradually impairing motor abilities, mental stability, ... A neurodegenerative condition called Huntington's disease (HD) damages the nerve cells in the brain, gradually impairing motor abilities, mental stability, and cognitive function. The huntingtin protein is produced in an aberrant form due to a mutation in the huntingtin gene (HTT) on chromosome 4. This mutant protein builds up in neurons, especially in the cerebral cortex and basal ganglia, causing malfunction and ultimately death.Huntington's disease symptoms can arise at any age, but they frequently manifest in adults, mainly between the ages of 30 and 50. Early symptoms frequently include chorea, or involuntary movements, which might start out mildly but eventually become more noticeable as the illness worsens. Daily duties can become difficult as a result of these motions, which can also impact the face, arms, legs, and other body parts.In addition to chorea, a variety of additional symptoms may be present in HD patients. These can include slurred speech, swallowing issues, behavioral and temperamental changes, and issues with balance and coordination. A major feature of the illness is cognitive decline, which impairs concentration, memory, and decision-making. As the illness progresses, people may need assistance with everyday tasks and ultimately become totally reliant on carers.While each case of Huntington's disease is different, the condition usually progresses in a progressive manner, with symptoms getting worse over time. As of right now, there is no known cure for HD; instead, quality of life is increased and symptoms are managed. In order to treat mood disorders and psychiatric symptoms, doctors may give antidepressants and antipsychotic medications. Tetrabenazine, for example, can help reduce involuntary movements. For those who are displaying symptoms or have a family history of Huntington's disease, genetic testing is an option. The choice to be tested, however, is quite personal because it affects the test-taker personally as well as their family. Genetic counseling is frequently advised to help people comprehend the advantages, disadvantages, and psychological effects of testing.The goal of ongoing research into Huntington's disease is to improve current therapies and eventually discover a cure. Support groups and other resources are offered in the interim to assist people with this difficult condition and their families in navigating its complexities and managing the effects it may have on their life.